Drag-reducing polyethylene oxide improves microcirculation after hemorrhagic shock

Abstract Background Despite resuscitation after trauma, microcirculatory abnormalities are known to persist in post-shock multiorgan dysfunction. The high-molecular weight polymer polyethylene oxide (PEO) (>106 Da), a classic drag-reducing polymer, can improve hemorrhagic shock (HS)–induced hemo...

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Veröffentlicht in:	The Journal of surgical research 2016-05, Vol.202 (1), p.118-125
Hauptverfasser:	Zeng, Zhenhua, PhD, Zhang, Qin, MM, Gao, Youguang, MD, Li, Tao, MM, Dai, Xingui, MD, Huang, Qiaobing, PhD, Chen, Zhongqing, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drag-reducing polymer (DRP) Hemorrhagic shock Infusions, Intravenous Kidney - blood supply Kidney - drug effects Liver - blood supply Liver - drug effects Lung - blood supply Lung - drug effects Male Microcirculation Microcirculation - drug effects Polyethylene Glycols - pharmacology Polyethylene Glycols - therapeutic use Polyethylene oxide Random Allocation Rats Rats, Sprague-Dawley Shock, Hemorrhagic - drug therapy Shock, Hemorrhagic - physiopathology Sprague–Dawley rats Surface-Active Agents - pharmacology Surface-Active Agents - therapeutic use Surgery Treatment Outcome
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