Anti-diabetic effect of 3-hydroxy-2-naphthoic acid, an endoplasmic reticulum stress-reducing chemical chaperone

Lots of experimental and clinical evidences indicate that chronic exposure to saturated fatty acids and high level of glucose is implicated in insulin resistance, beta cell failure and ultimately type 2 diabetes. In this study, we set up cell-based experimental conditions to induce endoplasmic retic...

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Veröffentlicht in:European journal of pharmacology 2016-05, Vol.779, p.157-167
Hauptverfasser: Park, Sun-mi, Choi, Jungsook, Nam, Tae-gyu, Ku, Jin-mo, Jeong, Kwiwan
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Sprache:eng
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