Hemorrhagic Cerebellar Abscess
Background Brain abscess represents a significant medical problem, accounting for 1 in every 10,000 U.S. hospital admissions and imposing a mortality of 17%–32%. Treatment success depends on early diagnosis, allowing for prompt intervention before a potentially catastrophic rupture. However, diagnos...
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description | Background Brain abscess represents a significant medical problem, accounting for 1 in every 10,000 U.S. hospital admissions and imposing a mortality of 17%–32%. Treatment success depends on early diagnosis, allowing for prompt intervention before a potentially catastrophic rupture. However, diagnosis can be difficult because currently no magnetic resonance imaging signal characteristics are pathognomonic. The presence of hemorrhage may further complicate the radiographic detection of an abscess, potentially leading to delayed treatment. Clinical Presentation A 71-year-old man was diagnosed with hemorrhagic cerebellar abscess as a complication of groin abscess after cardiac catheterization. After surgical resection of the cerebellar abscess and culture-based antibiotic treatment, the patient suffered repeat hemorrhages into the abscess cavity, of which he died. We describe his clinical course with emphasis on radiology-based differential diagnosis. We also describe the possible pathogenesis of this rare case, based on review of the literature. Conclusions To our knowledge, this is the first report on recurrent hemorrhages in a cerebellar abscess. Hemorrhagic brain abscess has a complex radiologic appearance, which may delay diagnosis and treatment. A high degree of clinical suspicion is necessary to ensure timely treatment of this potentially lethal lesion. |
doi_str_mv | 10.1016/j.wneu.2015.12.039 |
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Treatment success depends on early diagnosis, allowing for prompt intervention before a potentially catastrophic rupture. However, diagnosis can be difficult because currently no magnetic resonance imaging signal characteristics are pathognomonic. The presence of hemorrhage may further complicate the radiographic detection of an abscess, potentially leading to delayed treatment. Clinical Presentation A 71-year-old man was diagnosed with hemorrhagic cerebellar abscess as a complication of groin abscess after cardiac catheterization. After surgical resection of the cerebellar abscess and culture-based antibiotic treatment, the patient suffered repeat hemorrhages into the abscess cavity, of which he died. We describe his clinical course with emphasis on radiology-based differential diagnosis. We also describe the possible pathogenesis of this rare case, based on review of the literature. Conclusions To our knowledge, this is the first report on recurrent hemorrhages in a cerebellar abscess. Hemorrhagic brain abscess has a complex radiologic appearance, which may delay diagnosis and treatment. A high degree of clinical suspicion is necessary to ensure timely treatment of this potentially lethal lesion.</description><identifier>ISSN: 1878-8750</identifier><identifier>EISSN: 1878-8769</identifier><identifier>DOI: 10.1016/j.wneu.2015.12.039</identifier><identifier>PMID: 26724627</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Abscess ; Aged ; Brain Abscess - complications ; Brain Abscess - diagnosis ; Cerebellar Diseases - complications ; Cerebellar Diseases - diagnosis ; Cerebellum ; Cerebral Hemorrhage - complications ; Cerebral Hemorrhage - diagnosis ; Diagnosis, Differential ; Fatal Outcome ; Hemorrhage ; Humans ; Magnetic Resonance Imaging - methods ; Male ; Neurosurgery ; Tomography, X-Ray Computed - methods</subject><ispartof>World neurosurgery, 2016-04, Vol.88, p.692.e17-692.e22</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c432t-b7789030b2018e2db30588ede94b56e5adb9890abb050260dcd5a59388ff433e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.wneu.2015.12.039$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,778,782,3539,27913,27914,45984</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26724627$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Laviv, Yosef</creatorcontrib><creatorcontrib>Alterman, Ron</creatorcontrib><title>Hemorrhagic Cerebellar Abscess</title><title>World neurosurgery</title><addtitle>World Neurosurg</addtitle><description>Background Brain abscess represents a significant medical problem, accounting for 1 in every 10,000 U.S. hospital admissions and imposing a mortality of 17%–32%. Treatment success depends on early diagnosis, allowing for prompt intervention before a potentially catastrophic rupture. However, diagnosis can be difficult because currently no magnetic resonance imaging signal characteristics are pathognomonic. The presence of hemorrhage may further complicate the radiographic detection of an abscess, potentially leading to delayed treatment. Clinical Presentation A 71-year-old man was diagnosed with hemorrhagic cerebellar abscess as a complication of groin abscess after cardiac catheterization. After surgical resection of the cerebellar abscess and culture-based antibiotic treatment, the patient suffered repeat hemorrhages into the abscess cavity, of which he died. We describe his clinical course with emphasis on radiology-based differential diagnosis. We also describe the possible pathogenesis of this rare case, based on review of the literature. Conclusions To our knowledge, this is the first report on recurrent hemorrhages in a cerebellar abscess. Hemorrhagic brain abscess has a complex radiologic appearance, which may delay diagnosis and treatment. A high degree of clinical suspicion is necessary to ensure timely treatment of this potentially lethal lesion.</description><subject>Abscess</subject><subject>Aged</subject><subject>Brain Abscess - complications</subject><subject>Brain Abscess - diagnosis</subject><subject>Cerebellar Diseases - complications</subject><subject>Cerebellar Diseases - diagnosis</subject><subject>Cerebellum</subject><subject>Cerebral Hemorrhage - complications</subject><subject>Cerebral Hemorrhage - diagnosis</subject><subject>Diagnosis, Differential</subject><subject>Fatal Outcome</subject><subject>Hemorrhage</subject><subject>Humans</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Neurosurgery</subject><subject>Tomography, X-Ray Computed - methods</subject><issn>1878-8750</issn><issn>1878-8769</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUtLAzEUhYMottT-ARelSzcz5jGZZECEUtQKBRcquAuTzB3NOI-adJT-ezNUu3BhCCSLcw7nfhehc4Jjgkl6WcVfLfQxxYTHhMaYZUdoTKSQkRRpdnz4czxCU-8rHA4jiRTsFI1oKmiSUjFGsxU0nXNv-as18yU40FDXuZsvtDfg_Rk6KfPaw_TnnaDn25un5SpaP9zdLxfryCSMbiMthMwwwzrUkUALzTCXEgrIEs1T4HmhsyDItcYc0xQXpuA5z5iUZZkwBmyCLva5G9d99OC3qrGhQKjSQtd7RYQknPFE4iCle6lxnfcOSrVxtsndThGsBjSqUgMaNaBRhKqAJphmP_m9bqA4WH5BBMHVXgBhyk8LTnljoTVQWAdmq4rO_p9__cduattak9fvsANfdb1rAz9FlA8G9TgsZ9gNCVck7IV9A_VHh5c</recordid><startdate>20160401</startdate><enddate>20160401</enddate><creator>Laviv, Yosef</creator><creator>Alterman, Ron</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20160401</creationdate><title>Hemorrhagic Cerebellar Abscess</title><author>Laviv, Yosef ; Alterman, Ron</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c432t-b7789030b2018e2db30588ede94b56e5adb9890abb050260dcd5a59388ff433e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Abscess</topic><topic>Aged</topic><topic>Brain Abscess - complications</topic><topic>Brain Abscess - diagnosis</topic><topic>Cerebellar Diseases - complications</topic><topic>Cerebellar Diseases - diagnosis</topic><topic>Cerebellum</topic><topic>Cerebral Hemorrhage - complications</topic><topic>Cerebral Hemorrhage - diagnosis</topic><topic>Diagnosis, Differential</topic><topic>Fatal Outcome</topic><topic>Hemorrhage</topic><topic>Humans</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Neurosurgery</topic><topic>Tomography, X-Ray Computed - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Laviv, Yosef</creatorcontrib><creatorcontrib>Alterman, Ron</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>World neurosurgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Laviv, Yosef</au><au>Alterman, Ron</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hemorrhagic Cerebellar Abscess</atitle><jtitle>World neurosurgery</jtitle><addtitle>World Neurosurg</addtitle><date>2016-04-01</date><risdate>2016</risdate><volume>88</volume><spage>692.e17</spage><epage>692.e22</epage><pages>692.e17-692.e22</pages><issn>1878-8750</issn><eissn>1878-8769</eissn><abstract>Background Brain abscess represents a significant medical problem, accounting for 1 in every 10,000 U.S. hospital admissions and imposing a mortality of 17%–32%. Treatment success depends on early diagnosis, allowing for prompt intervention before a potentially catastrophic rupture. However, diagnosis can be difficult because currently no magnetic resonance imaging signal characteristics are pathognomonic. The presence of hemorrhage may further complicate the radiographic detection of an abscess, potentially leading to delayed treatment. Clinical Presentation A 71-year-old man was diagnosed with hemorrhagic cerebellar abscess as a complication of groin abscess after cardiac catheterization. After surgical resection of the cerebellar abscess and culture-based antibiotic treatment, the patient suffered repeat hemorrhages into the abscess cavity, of which he died. We describe his clinical course with emphasis on radiology-based differential diagnosis. We also describe the possible pathogenesis of this rare case, based on review of the literature. Conclusions To our knowledge, this is the first report on recurrent hemorrhages in a cerebellar abscess. Hemorrhagic brain abscess has a complex radiologic appearance, which may delay diagnosis and treatment. A high degree of clinical suspicion is necessary to ensure timely treatment of this potentially lethal lesion.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>26724627</pmid><doi>10.1016/j.wneu.2015.12.039</doi></addata></record> |
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subjects | Abscess Aged Brain Abscess - complications Brain Abscess - diagnosis Cerebellar Diseases - complications Cerebellar Diseases - diagnosis Cerebellum Cerebral Hemorrhage - complications Cerebral Hemorrhage - diagnosis Diagnosis, Differential Fatal Outcome Hemorrhage Humans Magnetic Resonance Imaging - methods Male Neurosurgery Tomography, X-Ray Computed - methods |
title | Hemorrhagic Cerebellar Abscess |
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