Transcatheter Therapies for Treating Tricuspid Regurgitation

Abstract Tricuspid valve (TV) disease has been relatively neglected, despite the known association between severe tricuspid regurgitation (TR) and mortality. Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with...

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Veröffentlicht in:Journal of the American College of Cardiology 2016-04, Vol.67 (15), p.1829-1845
Hauptverfasser: Rodés-Cabau, Josep, MD, Hahn, Rebecca T., MD, Latib, Azeem, MD, Laule, Michael, MD, Lauten, Alexander, MD, Maisano, Francesco, MD, Schofer, Joachim, MD, Campelo-Parada, Francisco, MD, Puri, Rishi, MBBS, PhD, Vahanian, Alec, MD
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container_end_page 1845
container_issue 15
container_start_page 1829
container_title Journal of the American College of Cardiology
container_volume 67
creator Rodés-Cabau, Josep, MD
Hahn, Rebecca T., MD
Latib, Azeem, MD
Laule, Michael, MD
Lauten, Alexander, MD
Maisano, Francesco, MD
Schofer, Joachim, MD
Campelo-Parada, Francisco, MD
Puri, Rishi, MBBS, PhD
Vahanian, Alec, MD
description Abstract Tricuspid valve (TV) disease has been relatively neglected, despite the known association between severe tricuspid regurgitation (TR) and mortality. Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with prior left-sided valve surgery. Patients with severe TR are often managed medically for years before TV repair or replacement. Current guidelines recommend TV repair in the presence of a dilated tricuspid annulus at the time of a left-sided valve surgical intervention, even if regurgitation is mild. This proposed algorithm aims to prevent the inevitable progression to severe TR and the need for a second surgical intervention. Recently, novel transcatheter treatment options were developed for treating patients with severe TR and right heart failure with prohibitive surgical risk. Here we describe currently available transcatheter treatment options for severe TR implanted at different levels: the junction between vena cavae and right atrium; the tricuspid annulus; or between TV leaflets, improving coaptation.
doi_str_mv 10.1016/j.jacc.2016.01.063
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Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with prior left-sided valve surgery. Patients with severe TR are often managed medically for years before TV repair or replacement. Current guidelines recommend TV repair in the presence of a dilated tricuspid annulus at the time of a left-sided valve surgical intervention, even if regurgitation is mild. This proposed algorithm aims to prevent the inevitable progression to severe TR and the need for a second surgical intervention. Recently, novel transcatheter treatment options were developed for treating patients with severe TR and right heart failure with prohibitive surgical risk. Here we describe currently available transcatheter treatment options for severe TR implanted at different levels: the junction between vena cavae and right atrium; the tricuspid annulus; or between TV leaflets, improving coaptation.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2016.01.063</identifier><identifier>PMID: 27081024</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>cardiac catheterization ; Cardiac Catheterization - methods ; Cardiology ; Cardiovascular ; Cardiovascular disease ; Disease Progression ; echocardiography ; Echocardiography - methods ; Heart attacks ; Heart failure ; Heart Valve Prosthesis Implantation - adverse effects ; Heart Valve Prosthesis Implantation - methods ; Hospital Mortality ; Hospitals ; Humans ; Hypertension ; Internal Medicine ; Mortality ; pulmonary hypertension ; right ventricular dysfunction ; Risk Adjustment ; Severity of Illness Index ; Surgery ; Time-to-Treatment ; tricuspid valve ; Tricuspid Valve - diagnostic imaging ; Tricuspid Valve - physiopathology ; Tricuspid Valve - surgery ; tricuspid valve insufficiency ; Tricuspid Valve Insufficiency - diagnosis ; Tricuspid Valve Insufficiency - mortality ; Tricuspid Valve Insufficiency - physiopathology ; Tricuspid Valve Insufficiency - surgery</subject><ispartof>Journal of the American College of Cardiology, 2016-04, Vol.67 (15), p.1829-1845</ispartof><rights>American College of Cardiology Foundation</rights><rights>2016 American College of Cardiology Foundation</rights><rights>Copyright © 2016 American College of Cardiology Foundation. 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Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with prior left-sided valve surgery. Patients with severe TR are often managed medically for years before TV repair or replacement. Current guidelines recommend TV repair in the presence of a dilated tricuspid annulus at the time of a left-sided valve surgical intervention, even if regurgitation is mild. This proposed algorithm aims to prevent the inevitable progression to severe TR and the need for a second surgical intervention. Recently, novel transcatheter treatment options were developed for treating patients with severe TR and right heart failure with prohibitive surgical risk. 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subjects cardiac catheterization
Cardiac Catheterization - methods
Cardiology
Cardiovascular
Cardiovascular disease
Disease Progression
echocardiography
Echocardiography - methods
Heart attacks
Heart failure
Heart Valve Prosthesis Implantation - adverse effects
Heart Valve Prosthesis Implantation - methods
Hospital Mortality
Hospitals
Humans
Hypertension
Internal Medicine
Mortality
pulmonary hypertension
right ventricular dysfunction
Risk Adjustment
Severity of Illness Index
Surgery
Time-to-Treatment
tricuspid valve
Tricuspid Valve - diagnostic imaging
Tricuspid Valve - physiopathology
Tricuspid Valve - surgery
tricuspid valve insufficiency
Tricuspid Valve Insufficiency - diagnosis
Tricuspid Valve Insufficiency - mortality
Tricuspid Valve Insufficiency - physiopathology
Tricuspid Valve Insufficiency - surgery
title Transcatheter Therapies for Treating Tricuspid Regurgitation
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