Transcatheter Therapies for Treating Tricuspid Regurgitation
Abstract Tricuspid valve (TV) disease has been relatively neglected, despite the known association between severe tricuspid regurgitation (TR) and mortality. Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with...
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Veröffentlicht in: | Journal of the American College of Cardiology 2016-04, Vol.67 (15), p.1829-1845 |
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creator | Rodés-Cabau, Josep, MD Hahn, Rebecca T., MD Latib, Azeem, MD Laule, Michael, MD Lauten, Alexander, MD Maisano, Francesco, MD Schofer, Joachim, MD Campelo-Parada, Francisco, MD Puri, Rishi, MBBS, PhD Vahanian, Alec, MD |
description | Abstract Tricuspid valve (TV) disease has been relatively neglected, despite the known association between severe tricuspid regurgitation (TR) and mortality. Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with prior left-sided valve surgery. Patients with severe TR are often managed medically for years before TV repair or replacement. Current guidelines recommend TV repair in the presence of a dilated tricuspid annulus at the time of a left-sided valve surgical intervention, even if regurgitation is mild. This proposed algorithm aims to prevent the inevitable progression to severe TR and the need for a second surgical intervention. Recently, novel transcatheter treatment options were developed for treating patients with severe TR and right heart failure with prohibitive surgical risk. Here we describe currently available transcatheter treatment options for severe TR implanted at different levels: the junction between vena cavae and right atrium; the tricuspid annulus; or between TV leaflets, improving coaptation. |
doi_str_mv | 10.1016/j.jacc.2016.01.063 |
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Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with prior left-sided valve surgery. Patients with severe TR are often managed medically for years before TV repair or replacement. Current guidelines recommend TV repair in the presence of a dilated tricuspid annulus at the time of a left-sided valve surgical intervention, even if regurgitation is mild. This proposed algorithm aims to prevent the inevitable progression to severe TR and the need for a second surgical intervention. Recently, novel transcatheter treatment options were developed for treating patients with severe TR and right heart failure with prohibitive surgical risk. Here we describe currently available transcatheter treatment options for severe TR implanted at different levels: the junction between vena cavae and right atrium; the tricuspid annulus; or between TV leaflets, improving coaptation.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2016.01.063</identifier><identifier>PMID: 27081024</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>cardiac catheterization ; Cardiac Catheterization - methods ; Cardiology ; Cardiovascular ; Cardiovascular disease ; Disease Progression ; echocardiography ; Echocardiography - methods ; Heart attacks ; Heart failure ; Heart Valve Prosthesis Implantation - adverse effects ; Heart Valve Prosthesis Implantation - methods ; Hospital Mortality ; Hospitals ; Humans ; Hypertension ; Internal Medicine ; Mortality ; pulmonary hypertension ; right ventricular dysfunction ; Risk Adjustment ; Severity of Illness Index ; Surgery ; Time-to-Treatment ; tricuspid valve ; Tricuspid Valve - diagnostic imaging ; Tricuspid Valve - physiopathology ; Tricuspid Valve - surgery ; tricuspid valve insufficiency ; Tricuspid Valve Insufficiency - diagnosis ; Tricuspid Valve Insufficiency - mortality ; Tricuspid Valve Insufficiency - physiopathology ; Tricuspid Valve Insufficiency - surgery</subject><ispartof>Journal of the American College of Cardiology, 2016-04, Vol.67 (15), p.1829-1845</ispartof><rights>American College of Cardiology Foundation</rights><rights>2016 American College of Cardiology Foundation</rights><rights>Copyright © 2016 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.</rights><rights>Copyright Elsevier Limited Apr 19, 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c549t-66798f9aebcf08f5ba89521176645ef8ca8dedeab803ee91574ec2e8b7d439e03</citedby><cites>FETCH-LOGICAL-c549t-66798f9aebcf08f5ba89521176645ef8ca8dedeab803ee91574ec2e8b7d439e03</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0735109716007117$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27081024$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rodés-Cabau, Josep, MD</creatorcontrib><creatorcontrib>Hahn, Rebecca T., MD</creatorcontrib><creatorcontrib>Latib, Azeem, MD</creatorcontrib><creatorcontrib>Laule, Michael, MD</creatorcontrib><creatorcontrib>Lauten, Alexander, MD</creatorcontrib><creatorcontrib>Maisano, Francesco, MD</creatorcontrib><creatorcontrib>Schofer, Joachim, MD</creatorcontrib><creatorcontrib>Campelo-Parada, Francisco, MD</creatorcontrib><creatorcontrib>Puri, Rishi, MBBS, PhD</creatorcontrib><creatorcontrib>Vahanian, Alec, MD</creatorcontrib><title>Transcatheter Therapies for Treating Tricuspid Regurgitation</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>Abstract Tricuspid valve (TV) disease has been relatively neglected, despite the known association between severe tricuspid regurgitation (TR) and mortality. Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with prior left-sided valve surgery. Patients with severe TR are often managed medically for years before TV repair or replacement. Current guidelines recommend TV repair in the presence of a dilated tricuspid annulus at the time of a left-sided valve surgical intervention, even if regurgitation is mild. This proposed algorithm aims to prevent the inevitable progression to severe TR and the need for a second surgical intervention. Recently, novel transcatheter treatment options were developed for treating patients with severe TR and right heart failure with prohibitive surgical risk. Here we describe currently available transcatheter treatment options for severe TR implanted at different levels: the junction between vena cavae and right atrium; the tricuspid annulus; or between TV leaflets, improving coaptation.</description><subject>cardiac catheterization</subject><subject>Cardiac Catheterization - methods</subject><subject>Cardiology</subject><subject>Cardiovascular</subject><subject>Cardiovascular disease</subject><subject>Disease Progression</subject><subject>echocardiography</subject><subject>Echocardiography - methods</subject><subject>Heart attacks</subject><subject>Heart failure</subject><subject>Heart Valve Prosthesis Implantation - adverse effects</subject><subject>Heart Valve Prosthesis Implantation - methods</subject><subject>Hospital Mortality</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypertension</subject><subject>Internal Medicine</subject><subject>Mortality</subject><subject>pulmonary hypertension</subject><subject>right ventricular dysfunction</subject><subject>Risk Adjustment</subject><subject>Severity of Illness Index</subject><subject>Surgery</subject><subject>Time-to-Treatment</subject><subject>tricuspid valve</subject><subject>Tricuspid Valve - diagnostic imaging</subject><subject>Tricuspid Valve - physiopathology</subject><subject>Tricuspid Valve - surgery</subject><subject>tricuspid valve insufficiency</subject><subject>Tricuspid Valve Insufficiency - diagnosis</subject><subject>Tricuspid Valve Insufficiency - mortality</subject><subject>Tricuspid Valve Insufficiency - physiopathology</subject><subject>Tricuspid Valve Insufficiency - surgery</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kU1r3DAQhkVo6G7S_oEcykIvudgZ2dYXLIUS8gULgWR7FrI83sj12lvJLuTfR84mLewhJ43E8w6jZwg5o5BSoPyiSRtjbZrFOgWaAs-PyJwyJpOcKfGJzEHkLKGgxIychNAAAJdUfSazTICkkBVzslx70wVrhicc0C_WT-jNzmFY1H28eTSD6zaxcHYMO1ctHnAz-o0b4nvffSHHtWkDfn07T8mv66v15W2yur-5u_y5Siwr1JBwLpSslcHS1iBrVhqpWEap4LxgWEtrZIUVmlJCjqgoEwXaDGUpqiJXCPkpOd_33fn-z4hh0FsXLLat6bAfg6ZCUpZnTMmIfj9Am370XZzulRKSSS4ile0p6_sQPNZ6593W-GdNQU9udaMnt3pyq4Hq6DaGvr21HsstVv8i7zIjsNwDGF38deh1sA47i5XzaAdd9e7j_j8O4rZ1nbOm_Y3PGP7_Q4dMg36ctjstl3IAEW3mL33Snr0</recordid><startdate>20160419</startdate><enddate>20160419</enddate><creator>Rodés-Cabau, Josep, MD</creator><creator>Hahn, Rebecca T., MD</creator><creator>Latib, Azeem, MD</creator><creator>Laule, Michael, MD</creator><creator>Lauten, Alexander, MD</creator><creator>Maisano, Francesco, MD</creator><creator>Schofer, Joachim, MD</creator><creator>Campelo-Parada, Francisco, MD</creator><creator>Puri, Rishi, MBBS, PhD</creator><creator>Vahanian, Alec, MD</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20160419</creationdate><title>Transcatheter Therapies for Treating Tricuspid Regurgitation</title><author>Rodés-Cabau, Josep, MD ; Hahn, Rebecca T., MD ; Latib, Azeem, MD ; Laule, Michael, MD ; Lauten, Alexander, MD ; Maisano, Francesco, MD ; Schofer, Joachim, MD ; Campelo-Parada, Francisco, MD ; Puri, Rishi, MBBS, PhD ; Vahanian, Alec, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c549t-66798f9aebcf08f5ba89521176645ef8ca8dedeab803ee91574ec2e8b7d439e03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>cardiac catheterization</topic><topic>Cardiac Catheterization - methods</topic><topic>Cardiology</topic><topic>Cardiovascular</topic><topic>Cardiovascular disease</topic><topic>Disease Progression</topic><topic>echocardiography</topic><topic>Echocardiography - methods</topic><topic>Heart attacks</topic><topic>Heart failure</topic><topic>Heart Valve Prosthesis Implantation - adverse effects</topic><topic>Heart Valve Prosthesis Implantation - methods</topic><topic>Hospital Mortality</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hypertension</topic><topic>Internal Medicine</topic><topic>Mortality</topic><topic>pulmonary hypertension</topic><topic>right ventricular dysfunction</topic><topic>Risk Adjustment</topic><topic>Severity of Illness Index</topic><topic>Surgery</topic><topic>Time-to-Treatment</topic><topic>tricuspid valve</topic><topic>Tricuspid Valve - diagnostic imaging</topic><topic>Tricuspid Valve - physiopathology</topic><topic>Tricuspid Valve - surgery</topic><topic>tricuspid valve insufficiency</topic><topic>Tricuspid Valve Insufficiency - diagnosis</topic><topic>Tricuspid Valve Insufficiency - mortality</topic><topic>Tricuspid Valve Insufficiency - physiopathology</topic><topic>Tricuspid Valve Insufficiency - surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rodés-Cabau, Josep, MD</creatorcontrib><creatorcontrib>Hahn, Rebecca T., MD</creatorcontrib><creatorcontrib>Latib, Azeem, MD</creatorcontrib><creatorcontrib>Laule, Michael, MD</creatorcontrib><creatorcontrib>Lauten, Alexander, MD</creatorcontrib><creatorcontrib>Maisano, Francesco, MD</creatorcontrib><creatorcontrib>Schofer, Joachim, MD</creatorcontrib><creatorcontrib>Campelo-Parada, Francisco, MD</creatorcontrib><creatorcontrib>Puri, Rishi, MBBS, PhD</creatorcontrib><creatorcontrib>Vahanian, Alec, MD</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rodés-Cabau, Josep, MD</au><au>Hahn, Rebecca T., MD</au><au>Latib, Azeem, MD</au><au>Laule, Michael, MD</au><au>Lauten, Alexander, MD</au><au>Maisano, Francesco, MD</au><au>Schofer, Joachim, MD</au><au>Campelo-Parada, Francisco, MD</au><au>Puri, Rishi, MBBS, PhD</au><au>Vahanian, Alec, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Transcatheter Therapies for Treating Tricuspid Regurgitation</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>2016-04-19</date><risdate>2016</risdate><volume>67</volume><issue>15</issue><spage>1829</spage><epage>1845</epage><pages>1829-1845</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><abstract>Abstract Tricuspid valve (TV) disease has been relatively neglected, despite the known association between severe tricuspid regurgitation (TR) and mortality. Few patients undergo isolated tricuspid surgery, which remains associated with high in-hospital mortality rates, particularly in patients with prior left-sided valve surgery. Patients with severe TR are often managed medically for years before TV repair or replacement. Current guidelines recommend TV repair in the presence of a dilated tricuspid annulus at the time of a left-sided valve surgical intervention, even if regurgitation is mild. This proposed algorithm aims to prevent the inevitable progression to severe TR and the need for a second surgical intervention. Recently, novel transcatheter treatment options were developed for treating patients with severe TR and right heart failure with prohibitive surgical risk. Here we describe currently available transcatheter treatment options for severe TR implanted at different levels: the junction between vena cavae and right atrium; the tricuspid annulus; or between TV leaflets, improving coaptation.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27081024</pmid><doi>10.1016/j.jacc.2016.01.063</doi><tpages>17</tpages><oa>free_for_read</oa></addata></record> |
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subjects | cardiac catheterization Cardiac Catheterization - methods Cardiology Cardiovascular Cardiovascular disease Disease Progression echocardiography Echocardiography - methods Heart attacks Heart failure Heart Valve Prosthesis Implantation - adverse effects Heart Valve Prosthesis Implantation - methods Hospital Mortality Hospitals Humans Hypertension Internal Medicine Mortality pulmonary hypertension right ventricular dysfunction Risk Adjustment Severity of Illness Index Surgery Time-to-Treatment tricuspid valve Tricuspid Valve - diagnostic imaging Tricuspid Valve - physiopathology Tricuspid Valve - surgery tricuspid valve insufficiency Tricuspid Valve Insufficiency - diagnosis Tricuspid Valve Insufficiency - mortality Tricuspid Valve Insufficiency - physiopathology Tricuspid Valve Insufficiency - surgery |
title | Transcatheter Therapies for Treating Tricuspid Regurgitation |
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