Clonal anergy induced in a CD8 super(+) hapten-specific cytotoxic T-cell clone by an altered hapten-peptide ligand

Clonal T-cell anergy has been proposed as a mechanism to ensure peripheral tolerance in vivo. Anergy has been reported to result from T cell activation with inappropriate antigen-presenting cells (APC) or, in the case of CD4 super(+) T cells, also by altered peptide ligands. This study reveals that...

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Veröffentlicht in:	Immunology 2001-01, Vol.102 (1), p.8-14
Hauptverfasser:	Preckel, T, Hellwig, S, Pflugfelder, U, Lappin, M B, Weltzien, HU
Format:	Artikel
Sprache:	eng
Schlagworte:	CD8 antigen
Online-Zugang:	Volltext
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