Adipose stem cells differentiated chondrocytes regenerate damaged cartilage in rat model of osteoarthritis

Transplantation of mesenchymal stem cells (MSCs) or autologous chondrocytes has been shown to repair damages to articular cartilage due to osteoarthritis (OA). However, survival of transplanted cells is considerably reduced in the osteoarthritic environment and it affects successful outcome of the t...

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Veröffentlicht in:	Cell biology international 2016-05, Vol.40 (5), p.579-588
Hauptverfasser:	Latief, Noreen, Raza, Fahad Ali, Bhatti, Fazal-Ur-Rehman, Tarar, Moazzam Nazir, Khan, Shaheen N., Riazuddin, Sheikh
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - metabolism Adipocytes - physiology Adipocytes - transplantation ADSCs Animals Cartilage, Articular - metabolism Cell Differentiation - physiology Cells, Cultured Chondrocytes - metabolism Chondrocytes - physiology Chondrogenesis DCs Disease Models, Animal Female Gene expression Mesenchymal Stem Cell Transplantation - methods Mesenchymal Stromal Cells - cytology osteoarthritis Osteoarthritis, Knee - pathology Osteoarthritis, Knee - therapy Proteoglycans - metabolism rat model of osteoarthritis Rats Rats, Sprague-Dawley Regeneration - physiology Rodents Stem cells
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