Antitumor and biological investigation of doubly cyclometalated ruthenium() organometallics derived from benzimidazolyl derivatives

In this study, we report the synthesis, anticancer and biological properties of three doubly cyclometalated phenylbenzimidazole derived ruthenium( ii ) organometallics ( 13 ) and their corresponding three organic ligands. The structures of 13 were fully characterized by various analytical techniques...

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Veröffentlicht in:	Dalton transactions : an international journal of inorganic chemistry 2016-04, Vol.45 (15), p.6667-6673
Hauptverfasser:	Elumalai, Palani, Jeong, Yong Joon, Park, Dae Won, Kim, Dong Hwan, Kim, Hyunuk, Kang, Se Chan, Chi, Ki-Whan
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antineoplastic Agents - chemical synthesis Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacology Benzimidazoles - chemistry Biological Cancer Cell Line, Tumor Cell Proliferation - drug effects Cytokines Cytokines - secretion Drug Screening Assays, Antitumor Drug Stability Drugs Genes Humans Ligands Metalorganic compounds Models, Molecular Molecular Conformation Organometallic Compounds - chemical synthesis Organometallic Compounds - chemistry Organometallic Compounds - pharmacology Ruthenium - chemistry Secretions
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