Biotransformation of dehydro-epi-androsterone by Aspergillus parasiticus: Metabolic evidences of BVMO activity

[Display omitted] •A. parasiticus oxidized the standard BVMO substrate, bicyclo[3.2.0]hept-2-en-6-one.•DHEA biotransformation outcome varied with O2 availability.•A. parasiticus converted cortisone to adrenosterone through an oxidative route.•Gathered evidences denote the occurrence of BVMO activity...

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Veröffentlicht in:	Steroids 2016-05, Vol.109, p.44-49
Hauptverfasser:	Mascotti, M. Laura, Palazzolo, Martín A., Bisogno, Fabricio R., Kurina-Sanz, Marcela
Format:	Artikel
Sprache:	eng
Schlagworte:	Aspergillus - enzymology Aspergillus - metabolism Aspergillus parasiticus Baeyer-Villiger monooxygenase Biotransformation Cortisone Dehydro-epi-androsterone Dehydroepiandrosterone - chemistry Dehydroepiandrosterone - metabolism Mixed Function Oxygenases - metabolism Steroids
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