Genomic alterations of the JAK2 and PDL loci occur in a broad spectrum of lymphoid malignancies

The recurrent 9p24.1 aberrations in lymphoid malignancies potentially involving four cancer‐related and druggable genes (JAK2, CD274/PDL1, PDCD1LG2/PDL2, and KDM4C/JMJD2Cl) are incompletely characterized. To gain more insight into the anatomy of these abnormalities, at first we studied 9p24.1 altera...

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Veröffentlicht in:	Genes chromosomes & cancer 2016-05, Vol.55 (5), p.428-441
Hauptverfasser:	Van Roosbroeck, Katrien, Ferreiro, Julio Finalet, Tousseyn, Thomas, van der Krogt, Jo-Anne, Michaux, Lucienne, Pienkowska-Grela, Barbara, Theate, Ivan, De Paepe, Pascale, Dierickx, Daan, Doyen, Chantal, Put, Natalie, Cools, Jan, Vandenberghe, Peter, Wlodarska, Iwona
Format:	Artikel
Sprache:	eng
Schlagworte:	B7-H1 Antigen - genetics Chromosome Banding Gene Expression Profiling Humans Janus Kinase 2 - genetics Karyotyping Lymphoma - genetics Mutation
Online-Zugang:	Volltext
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