Inhibitory effects of Aster spathulifolius extract on adipogenesis and lipid accumulation in 3T3-L1 preadipocytes

Objectives Aster spathulifolius Maxim (AS), known for its anti‐viral and anti‐allergic activity, is also known to reduce body weight gain in high fat diet‐induced obese rats. But its molecular mechanism of the anti‐obesity effects is still unclear. So, we investigated the inhibitory effect of AS ext...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2016-01, Vol.68 (1), p.107-118
Hauptverfasser:	Kim, Sa-Jic, Choung, Se-Young
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Adipocytes - drug effects Adipocytes - metabolism adipogenesis Adipogenesis - drug effects AMPKα Animals Aster Plant - chemistry Aster spathulifolius maxim CCAAT-Enhancer-Binding Protein-alpha - metabolism Cell Differentiation - drug effects Cell Line Down-Regulation - drug effects Lipid Metabolism - drug effects Lipids Mice Obesity - drug therapy Obesity - metabolism Phosphorylation - drug effects Plant Extracts - chemistry Plant Extracts - pharmacology PPAR gamma - metabolism PPAR-γ Rodents Signal Transduction - drug effects Studies Triglycerides - metabolism
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