MEP1A contributes to tumor progression and predicts poor clinical outcome in human hepatocellular carcinoma

Although many staging classifications have been proposed for hepatocellular carcinoma (HCC), determining a patient's prognosis in clinical practice is a challenge due to the molecular diversity of HCC. We investigated the relationship between MEP1A, a candidate oncogene, and clinical outcomes o...

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Veröffentlicht in:	Hepatology (Baltimore, Md.) Md.), 2016-04, Vol.63 (4), p.1227-1239
Hauptverfasser:	OuYang, Han‐Yue, Xu, Jing, Luo, Jun, Zou, Ru‐Hai, Chen, Keng, Le, Yong, Zhang, Yong‐Fa, Wei, Wei, Guo, Rong‐Ping, Shi, Ming
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Analysis of Variance Biomarkers, Tumor - blood Carcinoma, Hepatocellular - blood Carcinoma, Hepatocellular - mortality Carcinoma, Hepatocellular - pathology Carcinoma, Hepatocellular - surgery Cell proliferation Clinical outcomes Cohort Studies Confidence intervals Cytoskeleton Disease Progression Disease-Free Survival Female Hepatectomy - methods Hepatocellular carcinoma Hepatology Humans Kaplan-Meier Estimate Liver cancer Liver cirrhosis Liver diseases Liver Neoplasms - blood Liver Neoplasms - mortality Liver Neoplasms - parasitology Liver Neoplasms - surgery Male Medical prognosis Mesenchyme Metalloendopeptidases - metabolism Middle Aged mRNA Multivariate Analysis Neoplasm Invasiveness - pathology Neoplasm Staging Polymerase chain reaction Prognosis Proportional Hazards Models Real-Time Polymerase Chain Reaction - methods Retrospective Studies Risk Assessment RNA, Messenger - metabolism Statistics, Nonparametric Survival Analysis Treatment Outcome Tumor cells
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