Battling Alzheimer’s Disease: Targeting SUMOylation-Mediated Pathways

SUMO (small ubiquitin-like modifier) conjugation is a critically important control process in all eukaryotic cells, because it acts as a biochemical switch and regulates the function of hundreds of proteins in many different pathways. Although the diverse functional consequences and molecular target...

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Veröffentlicht in:	Neurochemical research 2016-03, Vol.41 (3), p.568-578
Hauptverfasser:	Martins, Wagner Carbolin, Tasca, Carla Inês, Cimarosti, Helena
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Alzheimer Disease - drug therapy Alzheimer Disease - metabolism Alzheimer's disease Animals Biochemistry Biomedical and Life Sciences Biomedicine Cell Biology Humans Molecular Targeted Therapy Neurochemistry Neurology Neurosciences Original Paper Signal Transduction Small Ubiquitin-Related Modifier Proteins - metabolism Sumoylation
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