Effectiveness of GK-2, a Nerve Growth Factor Mimetic, in Preventing Post-Resuscitation Changes in the Brain

Neurological status was assessed and the numbers of neurons per 1 mm in pyramidal neuronal layer length in CA1 and CA4 hippocampal fi elds and cerebellar Purkinje cells were evaluated in albino male rats on post-resuscitation day 14 after 12-min cardiac arrest. Intraperitoneal administration of GK-2...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2015-08, Vol.159 (4), p.453-455
Hauptverfasser:	Zarzhetskii, Yu. V., Avrushchenko, M. Sh, Moroz, V. V., Gudasheva, T. A., Seredenin, S. B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Brain CA1 Region, Hippocampal - drug effects CA1 Region, Hippocampal - pathology Cell Biology Cerebellum - drug effects Cerebellum - pathology Dentate Gyrus - drug effects Dentate Gyrus - pathology Dipeptides - pharmacology Drug Evaluation, Preclinical Internal Medicine Laboratory Medicine Male Molecular Mimicry Nerve growth factor Neurons Neuroprotective Agents - pharmacology Pathology Pyramidal Cells - drug effects Pyramidal Cells - pathology Rats Recovery of Function Resuscitation
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