Routine use of array comparative genomic hybridization (aCGH) as standard approach for prenatal diagnosis of chromosomal abnormalities. Clinical experience of 1763 prenatal cases

Objective This study aims to evaluate the diagnostic yield of comparative genomic hybridization microarrays (aCGH) and compare it with conventional karyotype analysis of standard >5‐Mb resolution. Method A total of 1763 prenatal samples were analyzed by aCGH (CytoChip Focus Constitutional microar...

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Veröffentlicht in:	Prenatal diagnosis 2015-12, Vol.35 (13), p.1269-1277
Hauptverfasser:	Papoulidis, Ioannis, Sotiriadis, Alexandros, Siomou, Elisavet, Papageorgiou, Elena, Eleftheriades, Makarios, Papadopoulos, Vasilios, Oikonomidou, Eirini, Orru, Sandro, Manolakos, Emmanouil, Athanasiadis, Apostolos
Format:	Artikel
Sprache:	eng
Schlagworte:	Chromosome Disorders - diagnosis Comparative Genomic Hybridization Female Humans Pregnancy Prenatal Diagnosis - methods
Online-Zugang:	Volltext
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