Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer: e0150564

Therapies targeting the type I insulin-like growth factor receptor (IGF-1R) have not been developed with predictive biomarkers to identify tumors with receptor activation. We have previously shown that the insulin receptor substrate (IRS) adaptor proteins are necessary for linking IGF1R to downstrea...

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Veröffentlicht in:PloS one 2016-03, Vol.11 (3)
Hauptverfasser: Becker, Marc A, Ibrahim, Yasir H, Oh, Annabell S, Fagan, Dedra H, Byron, Sara A, Sarver, Aaron L, Lee, Adrian V, Shaw, Leslie M, Fan, Cheng, Perou, Charles M
Format: Artikel
Sprache:eng
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