Effect of histamine H sub(2) receptor antagonism on levodopa-induced dyskinesia in the MPTP-macaque model of Parkinson's disease

Levodopa-induced motor complications, including dyskinesia and wearing off, are troublesome side effects of treatment and impair quality of life in Parkinson's disease (PD) patients. The use of nondopaminergic agents as adjuncts to levodopa are potential options for managing these problems. Her...

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Veröffentlicht in:Movement disorders 2010-07, Vol.25 (10), p.1379-1390
Hauptverfasser: Johnston, Tom H, van der Meij, Anne, Brotchie, Jonathan M, Fox, Susan H
Format: Artikel
Sprache:eng
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