Variability of the Phenotype and Proliferation and Migration Characteristics of Human Mesenchymal Stromal Cells Derived from the Deciduous Teeth Pulp of Different Donors
We performed a comparative study of cell phenotype and proliferation and migration activities in vitro of mesenchymal stromal cells from human exfoliated deciduous teeth (SHED cells) from three donors. In the primary cultures, the cells of different donors had the same morphology and cytophenotype,...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 2016-02, Vol.160 (4), p.525-529 |
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| container_title | Bulletin of experimental biology and medicine |
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| creator | Vakhrushev, I. V. Vdovin, A. S. Strukova, L. A. Yarygin, K. N. |
| description | We performed a comparative study of cell phenotype and proliferation and migration activities
in vitro
of mesenchymal stromal cells from human exfoliated deciduous teeth (SHED cells) from three donors. In the primary cultures, the cells of different donors had the same morphology and cytophenotype, but differed by proliferative and migration capacities. The results indicate that individual mesenchymal stromal cells cultures can differ considerably by important cell properties, and this should be considered when evaluating their potential therapeutic efficacy and in experimental studies. |
| doi_str_mv | 10.1007/s10517-016-3212-x |
| format | Article |
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in vitro
of mesenchymal stromal cells from human exfoliated deciduous teeth (SHED cells) from three donors. In the primary cultures, the cells of different donors had the same morphology and cytophenotype, but differed by proliferative and migration capacities. The results indicate that individual mesenchymal stromal cells cultures can differ considerably by important cell properties, and this should be considered when evaluating their potential therapeutic efficacy and in experimental studies.</description><identifier>ISSN: 0007-4888</identifier><identifier>EISSN: 1573-8221</identifier><identifier>DOI: 10.1007/s10517-016-3212-x</identifier><identifier>PMID: 26899847</identifier><identifier>CODEN: BEXBAN</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Biomedical and Life Sciences ; Biomedicine ; Cell Biology ; Cell Differentiation - physiology ; Cell Proliferation - physiology ; Cell- and Tissue-Based Therapy ; Cells, Cultured ; Child ; Child, Preschool ; Dental Pulp - cytology ; Female ; Genetic aspects ; Health aspects ; Humans ; Internal Medicine ; Laboratory Medicine ; Male ; Mesenchymal Stromal Cells - cytology ; Pathology ; Phenotype ; Stem cells ; Tooth, Deciduous - cytology</subject><ispartof>Bulletin of experimental biology and medicine, 2016-02, Vol.160 (4), p.525-529</ispartof><rights>Springer Science+Business Media New York 2016</rights><rights>COPYRIGHT 2016 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-df14ca9d21ff459ec362cc77780508fbf68e41c7127050c929ed30fb80f7d6fb3</citedby><cites>FETCH-LOGICAL-c503t-df14ca9d21ff459ec362cc77780508fbf68e41c7127050c929ed30fb80f7d6fb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10517-016-3212-x$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10517-016-3212-x$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>315,781,785,27928,27929,41492,42561,51323</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26899847$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Vakhrushev, I. V.</creatorcontrib><creatorcontrib>Vdovin, A. S.</creatorcontrib><creatorcontrib>Strukova, L. A.</creatorcontrib><creatorcontrib>Yarygin, K. N.</creatorcontrib><title>Variability of the Phenotype and Proliferation and Migration Characteristics of Human Mesenchymal Stromal Cells Derived from the Deciduous Teeth Pulp of Different Donors</title><title>Bulletin of experimental biology and medicine</title><addtitle>Bull Exp Biol Med</addtitle><addtitle>Bull Exp Biol Med</addtitle><description>We performed a comparative study of cell phenotype and proliferation and migration activities
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of mesenchymal stromal cells from human exfoliated deciduous teeth (SHED cells) from three donors. In the primary cultures, the cells of different donors had the same morphology and cytophenotype, but differed by proliferative and migration capacities. The results indicate that individual mesenchymal stromal cells cultures can differ considerably by important cell properties, and this should be considered when evaluating their potential therapeutic efficacy and in experimental studies.</description><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cell Biology</subject><subject>Cell Differentiation - physiology</subject><subject>Cell Proliferation - physiology</subject><subject>Cell- and Tissue-Based Therapy</subject><subject>Cells, Cultured</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Dental Pulp - cytology</subject><subject>Female</subject><subject>Genetic aspects</subject><subject>Health aspects</subject><subject>Humans</subject><subject>Internal Medicine</subject><subject>Laboratory Medicine</subject><subject>Male</subject><subject>Mesenchymal Stromal Cells - cytology</subject><subject>Pathology</subject><subject>Phenotype</subject><subject>Stem cells</subject><subject>Tooth, Deciduous - cytology</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqNks1u1DAUhSMEokPhAdggS0iomxTb-bGzrGYoRWrFSBS2luNcT1wl9mA7qPNIvCVOZ4AWgYS8sHzzneN745NlLwk-JRizt4HgirAckzovKKH57aNsQSpW5JxS8jhb4ATlJef8KHsWws18xDV5mh3RmjcNL9ki-_5FeiNbM5i4Q06j2ANa92Bd3G0BSduhtXeD0eBlNM7eVa7M5nBa9tJLFcGbEI0Ks8HFNEqLriCAVf1ulAP6FL2b9yUMQ0CrBH-DDulUvLttBcp0k5sCugaIPVpPw3Y2WhmdbgUb0cpZ58Pz7ImWQ4AXh_04-3z-7np5kV9-fP9heXaZqwoXMe80KZVsOkq0LqsGVFFTpRhjHFeY61bXHEqiGKEsFVRDG-gKrFuONetq3RbH2cned-vd1wlCFKMJKvUuLaQuBZmdSJHk_4EyzBlLbST09R_ojZu8TYPMFCG4wZT-pjZyAGGsdjH939lUnJUVLZuyqlmiTv9CpdXBaJSzoE2qPxC8uSfoQQ6xD26Y5jcMD0GyB5V3IXjQYuvNKP1OECzmyIl95ESKnJgjJ26T5tVhsqkdoful-JmxBNA9ENInuwF_b_R_uv4AbAThXQ</recordid><startdate>20160201</startdate><enddate>20160201</enddate><creator>Vakhrushev, I. 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V. ; Vdovin, A. S. ; Strukova, L. A. ; Yarygin, K. 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of mesenchymal stromal cells from human exfoliated deciduous teeth (SHED cells) from three donors. In the primary cultures, the cells of different donors had the same morphology and cytophenotype, but differed by proliferative and migration capacities. The results indicate that individual mesenchymal stromal cells cultures can differ considerably by important cell properties, and this should be considered when evaluating their potential therapeutic efficacy and in experimental studies.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>26899847</pmid><doi>10.1007/s10517-016-3212-x</doi><tpages>5</tpages></addata></record> |
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| subjects | Biomedical and Life Sciences Biomedicine Cell Biology Cell Differentiation - physiology Cell Proliferation - physiology Cell- and Tissue-Based Therapy Cells, Cultured Child Child, Preschool Dental Pulp - cytology Female Genetic aspects Health aspects Humans Internal Medicine Laboratory Medicine Male Mesenchymal Stromal Cells - cytology Pathology Phenotype Stem cells Tooth, Deciduous - cytology |
| title | Variability of the Phenotype and Proliferation and Migration Characteristics of Human Mesenchymal Stromal Cells Derived from the Deciduous Teeth Pulp of Different Donors |
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