Effect of chemical penetration enhancer on transdermal iontophoretic delivery of diclofenac sodium under constant voltage

The study aimed to enhance the transdermal permeation of diclofenac sodium using combined strategy of constant voltage iontophoresis (CVI) and chemical penetration enhancers (CPE). Four hydrogels of diclofenac sodium were formulated with the key CPE and hydroxyethyl cellulose (HEC) as a viscosity im...

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Veröffentlicht in:Journal of drug delivery science and technology 2015-12, Vol.30, p.171-179
Hauptverfasser: Arunkumar, S., Ashok, Purnima, Desai, B.G., Shivakumar, H.N.
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Sprache:eng
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