What Have We Learned From Brain Functional Connectivity Studies in Migraine Headache?

Over the past 20 years, headache syndromes, especially migraine, have benefited significantly from the knowledge gained through neuroimaging studies. This article is focused on the neuroimaging studies of the functional organization and connectivity of the migraine brain. First, data sources and the...

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Veröffentlicht in:Headache 2016-03, Vol.56 (3), p.453-461
Hauptverfasser: Maleki, Nasim, Gollub, Randy L.
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description Over the past 20 years, headache syndromes, especially migraine, have benefited significantly from the knowledge gained through neuroimaging studies. This article is focused on the neuroimaging studies of the functional organization and connectivity of the migraine brain. First, data sources and the study design elements in functional neuroimaging studies of the brain connectivity in migraine headaches are discussed. Then, the article reviews the findings to date and discusses how functional connectivity studies have contributed to a better understanding of the mechanisms of the migraine disease by extending the focus from a single region or structure to a network of regions and structures and the interactions among them. Finally, the potential scenarios for the translation of connectivity knowledge to the benefit for patients are discussed.
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subjects Brain - physiopathology
Brain Mapping - methods
Brain research
functional connectivity
functional magnetic resonance imaging
Functional Neuroimaging
Humans
Medical imaging
Migraine
Migraine Disorders - physiopathology
regional homogeneity
resting state networks
Studies
title What Have We Learned From Brain Functional Connectivity Studies in Migraine Headache?
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