Anti-Neoplastic Cytotoxicity of SN-38-Loaded PCL/Gelatin Electrospun Composite Nanofiber Scaffolds against Human Glioblastoma Cells In Vitro

Electrospun poly(ε-caprolactone) (PCL)/gelatin (GT) scaffolds were developed to provide controlled release of 7-ethyl-10-hydroxy camptothecin (SN-38). Acetic acid was introduced to improve the miscibility of PCL and GT to produce a homogeneous nanofiber membrane mixture. The effect of SN-38 content...

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Veröffentlicht in:Journal of pharmaceutical sciences 2015-12, Vol.104 (12), p.4345-4354
Hauptverfasser: Zhu, Xiaodong, Ni, Shilei, Xia, Tongliang, Yao, Qingyu, Li, Haoyuan, Wang, Benlin, Wang, Jiangang, Li, Xingang, Su, Wandong
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Sprache:eng
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