Metabolic syndrome in Moroccan patients with psoriasis
Background Several recent reports have shown a significant association between psoriasis and metabolic syndrome (MBS). Objective The goal of this study was to investigate the prevalence of MBS and, in particular, the main factors that determine this syndrome in Moroccan patients with psoriasis. Meth...
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| Veröffentlicht in: | International journal of dermatology 2016-04, Vol.55 (4), p.396-400 |
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| container_title | International journal of dermatology |
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| creator | Meziane, Mariame Kelati, Awatef Najdi, Adil Berraho, Amine Nejjari, Chakib Mernissi, Fatim-Zahra |
| description | Background
Several recent reports have shown a significant association between psoriasis and metabolic syndrome (MBS).
Objective
The goal of this study was to investigate the prevalence of MBS and, in particular, the main factors that determine this syndrome in Moroccan patients with psoriasis.
Methods
A case–control study has included 150 patients with psoriasis and 300 controls matched for age and sex, the MBS was defined according to the International Diabetes Foundation, and the severity of psoriasis was assessed by body surface area.
Results
Mild psoriasis was seen in 10.7%, 40.3% had moderate psoriasis, and 49% had severe psoriasis. MBS was higher in cases than in controls with statistical differences (44.7 vs. 2.7%, odds ratio [OR]: 26 CI: [12.4–54.3]; P = 0.000). Abdominal obesity and dyslipidemia were the only metabolic factors significantly related to psoriasis whereas diabetes, hypertension, smoking, alcohol consumption, and cardiovascular diseases were not significant. MBS increases with age in our patients with psoriasis, whereas there was no relationship between MBS and gender. Hypertension (P = 0.007), diabetes (P = 0.003), and increased level of triglycerides (P = 0.05) and high‐density lipoprotein cholesterol (P = 0.003) were associated with the severity of psoriasis.
Conclusion
Metabolic syndrome is an important comorbidity in patients with psoriasis, and vigilance and enhanced screening may be important in this population, especially patients with severe disease. |
| doi_str_mv | 10.1111/ijd.12623 |
| format | Article |
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Several recent reports have shown a significant association between psoriasis and metabolic syndrome (MBS).
Objective
The goal of this study was to investigate the prevalence of MBS and, in particular, the main factors that determine this syndrome in Moroccan patients with psoriasis.
Methods
A case–control study has included 150 patients with psoriasis and 300 controls matched for age and sex, the MBS was defined according to the International Diabetes Foundation, and the severity of psoriasis was assessed by body surface area.
Results
Mild psoriasis was seen in 10.7%, 40.3% had moderate psoriasis, and 49% had severe psoriasis. MBS was higher in cases than in controls with statistical differences (44.7 vs. 2.7%, odds ratio [OR]: 26 CI: [12.4–54.3]; P = 0.000). Abdominal obesity and dyslipidemia were the only metabolic factors significantly related to psoriasis whereas diabetes, hypertension, smoking, alcohol consumption, and cardiovascular diseases were not significant. MBS increases with age in our patients with psoriasis, whereas there was no relationship between MBS and gender. Hypertension (P = 0.007), diabetes (P = 0.003), and increased level of triglycerides (P = 0.05) and high‐density lipoprotein cholesterol (P = 0.003) were associated with the severity of psoriasis.
Conclusion
Metabolic syndrome is an important comorbidity in patients with psoriasis, and vigilance and enhanced screening may be important in this population, especially patients with severe disease.</description><identifier>ISSN: 0011-9059</identifier><identifier>EISSN: 1365-4632</identifier><identifier>DOI: 10.1111/ijd.12623</identifier><identifier>PMID: 26712557</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Adult ; Age Factors ; Alcohol Drinking - epidemiology ; Case-Control Studies ; Comorbidity ; Diabetes Mellitus - epidemiology ; Dyslipidemias - epidemiology ; Female ; Humans ; Hypertension - epidemiology ; Male ; Metabolic Syndrome - epidemiology ; Middle Aged ; Morocco - epidemiology ; Obesity, Abdominal - epidemiology ; Prevalence ; Psoriasis - epidemiology ; Severity of Illness Index ; Sex Factors ; Smoking - epidemiology</subject><ispartof>International journal of dermatology, 2016-04, Vol.55 (4), p.396-400</ispartof><rights>2015</rights><rights>2015 The International Society of Dermatology.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fijd.12623$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fijd.12623$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26712557$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Meziane, Mariame</creatorcontrib><creatorcontrib>Kelati, Awatef</creatorcontrib><creatorcontrib>Najdi, Adil</creatorcontrib><creatorcontrib>Berraho, Amine</creatorcontrib><creatorcontrib>Nejjari, Chakib</creatorcontrib><creatorcontrib>Mernissi, Fatim-Zahra</creatorcontrib><title>Metabolic syndrome in Moroccan patients with psoriasis</title><title>International journal of dermatology</title><addtitle>Int J Dermatol</addtitle><description>Background
Several recent reports have shown a significant association between psoriasis and metabolic syndrome (MBS).
Objective
The goal of this study was to investigate the prevalence of MBS and, in particular, the main factors that determine this syndrome in Moroccan patients with psoriasis.
Methods
A case–control study has included 150 patients with psoriasis and 300 controls matched for age and sex, the MBS was defined according to the International Diabetes Foundation, and the severity of psoriasis was assessed by body surface area.
Results
Mild psoriasis was seen in 10.7%, 40.3% had moderate psoriasis, and 49% had severe psoriasis. MBS was higher in cases than in controls with statistical differences (44.7 vs. 2.7%, odds ratio [OR]: 26 CI: [12.4–54.3]; P = 0.000). Abdominal obesity and dyslipidemia were the only metabolic factors significantly related to psoriasis whereas diabetes, hypertension, smoking, alcohol consumption, and cardiovascular diseases were not significant. MBS increases with age in our patients with psoriasis, whereas there was no relationship between MBS and gender. Hypertension (P = 0.007), diabetes (P = 0.003), and increased level of triglycerides (P = 0.05) and high‐density lipoprotein cholesterol (P = 0.003) were associated with the severity of psoriasis.
Conclusion
Metabolic syndrome is an important comorbidity in patients with psoriasis, and vigilance and enhanced screening may be important in this population, especially patients with severe disease.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Alcohol Drinking - epidemiology</subject><subject>Case-Control Studies</subject><subject>Comorbidity</subject><subject>Diabetes Mellitus - epidemiology</subject><subject>Dyslipidemias - epidemiology</subject><subject>Female</subject><subject>Humans</subject><subject>Hypertension - epidemiology</subject><subject>Male</subject><subject>Metabolic Syndrome - epidemiology</subject><subject>Middle Aged</subject><subject>Morocco - epidemiology</subject><subject>Obesity, Abdominal - epidemiology</subject><subject>Prevalence</subject><subject>Psoriasis - epidemiology</subject><subject>Severity of Illness Index</subject><subject>Sex Factors</subject><subject>Smoking - epidemiology</subject><issn>0011-9059</issn><issn>1365-4632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkD1PwzAQhi0EoqUw8AdQRpa0ti-24xHx0RalRUigSiyW4zjCJU1KnKr035N-0Jlb7k73vDc8CF0T3CdtDdw86xPKKZygLgHOwogDPUVdjAkJJWaygy68n7crUBKdow7lglDGRBfxiW10WhXOBH5TZnW1sIErg0lVV8boMljqxtmy8cHaNZ_B0le10975S3SW68Lbq0Pvofenx7f7UZi8DMf3d0noQFIIRZ5HTGvGbYw5RLmh3EoGUuosBpsSKqyQxmChITeWCKm1NDK1EclEmmEBPXS7_7usq--V9Y1aOG9sUejSViuviIgxwyQm8A9UQER5DFv05oCu0oXN1LJ2C11v1J-WFhjsgbUr7OZ4J1htfavWt9r5VuPnh93QJsJ9wvnG_hwTuv5SXIBgajYdqtcJHs2mH4lK4BdRrIBq</recordid><startdate>201604</startdate><enddate>201604</enddate><creator>Meziane, Mariame</creator><creator>Kelati, Awatef</creator><creator>Najdi, Adil</creator><creator>Berraho, Amine</creator><creator>Nejjari, Chakib</creator><creator>Mernissi, Fatim-Zahra</creator><general>Blackwell Publishing Ltd</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>201604</creationdate><title>Metabolic syndrome in Moroccan patients with psoriasis</title><author>Meziane, Mariame ; Kelati, Awatef ; Najdi, Adil ; Berraho, Amine ; Nejjari, Chakib ; Mernissi, Fatim-Zahra</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i3923-7ff45aa56e80634fc26e95399ad83eb127e79cc07a3fce179aa9c9be41d7bd073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Alcohol Drinking - epidemiology</topic><topic>Case-Control Studies</topic><topic>Comorbidity</topic><topic>Diabetes Mellitus - epidemiology</topic><topic>Dyslipidemias - epidemiology</topic><topic>Female</topic><topic>Humans</topic><topic>Hypertension - epidemiology</topic><topic>Male</topic><topic>Metabolic Syndrome - epidemiology</topic><topic>Middle Aged</topic><topic>Morocco - epidemiology</topic><topic>Obesity, Abdominal - epidemiology</topic><topic>Prevalence</topic><topic>Psoriasis - epidemiology</topic><topic>Severity of Illness Index</topic><topic>Sex Factors</topic><topic>Smoking - epidemiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Meziane, Mariame</creatorcontrib><creatorcontrib>Kelati, Awatef</creatorcontrib><creatorcontrib>Najdi, Adil</creatorcontrib><creatorcontrib>Berraho, Amine</creatorcontrib><creatorcontrib>Nejjari, Chakib</creatorcontrib><creatorcontrib>Mernissi, Fatim-Zahra</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>International journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Meziane, Mariame</au><au>Kelati, Awatef</au><au>Najdi, Adil</au><au>Berraho, Amine</au><au>Nejjari, Chakib</au><au>Mernissi, Fatim-Zahra</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Metabolic syndrome in Moroccan patients with psoriasis</atitle><jtitle>International journal of dermatology</jtitle><addtitle>Int J Dermatol</addtitle><date>2016-04</date><risdate>2016</risdate><volume>55</volume><issue>4</issue><spage>396</spage><epage>400</epage><pages>396-400</pages><issn>0011-9059</issn><eissn>1365-4632</eissn><abstract>Background
Several recent reports have shown a significant association between psoriasis and metabolic syndrome (MBS).
Objective
The goal of this study was to investigate the prevalence of MBS and, in particular, the main factors that determine this syndrome in Moroccan patients with psoriasis.
Methods
A case–control study has included 150 patients with psoriasis and 300 controls matched for age and sex, the MBS was defined according to the International Diabetes Foundation, and the severity of psoriasis was assessed by body surface area.
Results
Mild psoriasis was seen in 10.7%, 40.3% had moderate psoriasis, and 49% had severe psoriasis. MBS was higher in cases than in controls with statistical differences (44.7 vs. 2.7%, odds ratio [OR]: 26 CI: [12.4–54.3]; P = 0.000). Abdominal obesity and dyslipidemia were the only metabolic factors significantly related to psoriasis whereas diabetes, hypertension, smoking, alcohol consumption, and cardiovascular diseases were not significant. MBS increases with age in our patients with psoriasis, whereas there was no relationship between MBS and gender. Hypertension (P = 0.007), diabetes (P = 0.003), and increased level of triglycerides (P = 0.05) and high‐density lipoprotein cholesterol (P = 0.003) were associated with the severity of psoriasis.
Conclusion
Metabolic syndrome is an important comorbidity in patients with psoriasis, and vigilance and enhanced screening may be important in this population, especially patients with severe disease.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>26712557</pmid><doi>10.1111/ijd.12623</doi><tpages>5</tpages></addata></record> |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Age Factors Alcohol Drinking - epidemiology Case-Control Studies Comorbidity Diabetes Mellitus - epidemiology Dyslipidemias - epidemiology Female Humans Hypertension - epidemiology Male Metabolic Syndrome - epidemiology Middle Aged Morocco - epidemiology Obesity, Abdominal - epidemiology Prevalence Psoriasis - epidemiology Severity of Illness Index Sex Factors Smoking - epidemiology |
| title | Metabolic syndrome in Moroccan patients with psoriasis |
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