Phthalic acid mimics 17β-estradiol actions in WISH cells

The object of this study was to evaluate whether phthalic acid, which is one of the metabolites of phthalic acid esters, exerts estrogenic actions in WISH cells, an immortalized cell line derived from human amniotic tissue. Our data demonstrate that phthalic acid (i) displaces [ 3H]estradiol from it...

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Veröffentlicht in:	Toxicology letters 2001-01, Vol.118 (3), p.157-164
Hauptverfasser:	Pavan, B, Biondi, C, Ferretti, M.E, Lunghi, L, Paganetto, G
Format:	Artikel
Sprache:	eng
Schlagworte:	17β-Estradiol receptors Biological and medical sciences Chemical and industrial products toxicology. Toxic occupational diseases Cyclic AMP system Medical sciences Phthalic acid phthalic acid esters Prostaglandin release Toxicology Various organic compounds WISH cells xenoestrogens
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