Presence of commensal house dust mite allergen in human gastrointestinal tract: a potential contributor to intestinal barrier dysfunction

BackgroundAbnormal gut barrier function is the basis of gut inflammatory disease. It is known that house dust mite (HDM) aero-allergens induce inflammation in respiratory mucosa. We have recently reported allergen from Dermatophagoides pteronyssinus (Der p1) to be present in rodent gut.ObjectiveTo e...

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Veröffentlicht in:	Gut 2016-05, Vol.65 (5), p.757-766
Hauptverfasser:	Tulic, Meri K, Vivinus-Nébot, Mylene, Rekima, Akila, Rabelo Medeiros, Samara, Bonnart, Chrystelle, Shi, Haining, Walker, Allan, Dainese, Raffaella, Boyer, Julien, Vergnolle, Nathalie, Piche, Thierry, Verhasselt, Valérie
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens Allergies Animals Antigens Antigens, Dermatophagoides - isolation & purification Asymptomatic Biopsy Colon Cytokines Dermatophagoides pteronyssinus - immunology Disease prevention Endoscopy Gastrointestinal Diseases - immunology Gastrointestinal Tract - immunology Humans Inflammation Inflammatory diseases Mice Mice, Inbred BALB C Patients Permeability Proteins
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