Dissecting Electrostatic Contributions to Folding and Self-Assembly Using Designed Multicomponent Peptide Systems

We investigate formation of nano- to microscale peptide fibers and sheets where assembly requires association of two distinct collagen mimetic peptides (CMPs). The multicomponent nature of these designs allows the decoupling of amino acid contributions to peptide folding versus higher-order assembly...

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Veröffentlicht in:	Journal of the American Chemical Society 2016-04, Vol.138 (13), p.4362-4367
Hauptverfasser:	Parmar, Avanish S, James, Jose K, Grisham, Daniel R, Pike, Douglas H, Nanda, Vikas
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Biomimetics Collagen - chemistry Lysine - chemistry Models, Molecular Peptides - chemistry Static Electricity
Online-Zugang:	Volltext
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