Tissue accumulation and urinary excretion of Cr in chromium picolinate (CrPic)-supplemented lambs

[Display omitted] •We used ICP–MS and 52Cr as collected mass to measure Cr in tissue.•There is a relationship between dose and Cr in the heart, lung and testis.•Urinary excretion of Cr occurred in a time and dose-dependent manner.•There is a risk of bioaccumulation due to Cr offered as CrPic in the...

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Veröffentlicht in:	Journal of trace elements in medicine and biology 2016-05, Vol.35, p.30-35
Hauptverfasser:	Dallago, Bruno Stéfano Lima, Lima, Bárbara Alcântara Ferreira, Braz, Shélida Vasconcelos, Mustafa, Vanessa da Silva, McManus, Concepta, Paim, Tiago do Prado, Campeche, Aline, Gomes, Edgard Franco, Louvandini, Helder
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bioaccumulation Biodistribution Chromium - urine Dietary Supplements ICP–MS Male Mineral supplement Organ Specificity - drug effects Picolinic Acids - pharmacology Regression Analysis Santa Inês Sheep Tissue Distribution - drug effects
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