Progressive developmental restriction, acquisition of left-right identity and cell growth behavior during lobe formation in mouse liver development

To identify cell-based decisions implicated in morphogenesis of the mammalian liver, we performed clonal analysis of hepatocytes/hepatoblasts in mouse liver development, using a knock-in allele of Hnf4a/laacZ This transgene randomly undergoes a low frequency of recombination that generates a functio...

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Veröffentlicht in:Development (Cambridge) 2016-04, Vol.143 (7), p.1149-1159
Hauptverfasser: Weiss, Mary C, Le Garrec, Jean-Francois, Coqueran, Sabrina, Strick-Marchand, Helene, Buckingham, Margaret
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Sprache:eng
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