SATB1 promotes prostate cancer metastasis by the regulation of epithelial–mesenchymal transition

Abstract Special AT-rich sequence binding protein 1 (SATB1) plays important role in the regulation of chromatin structure and gene expression. Recent studies have indicated oncogenic role of SATB1. However, the function of SATB1 in prostate cancer progression and metastasis remains unclear. In this...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2016-04, Vol.79, p.1-8
Hauptverfasser:	Mao, Li-jun, Yang, Chun-hua, Fan, Li, Gao, Peng, Yang, Dong-rong, Xue, Bo-xin, Zheng, Jun-nian, Shan, Yu-xi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers, Tumor - metabolism Cadherins - metabolism Cell Line, Tumor Cell Proliferation Epithelial-Mesenchymal Transition Gene Expression Regulation, Neoplastic Gene Silencing Internal Medicine Invasion Male Matrix Attachment Region Binding Proteins - genetics Matrix Attachment Region Binding Proteins - metabolism Matrix Metalloproteinase 2 - metabolism Medical Education Metastasis Mice, Inbred BALB C Mice, Nude Neoplasm Metastasis Proliferation Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology SATB1 Subcutaneous Tissue - pathology Vimentin - metabolism Xenograft Model Antitumor Assays
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