Formulation of Acid-Sensitive Micelles for Delivery of Cabazitaxel into Prostate Cancer Cells

We report the synthesis of an amphiphilic triblock copolymer composed of a hydrophilic poly­(ethylene glycol) (PEG) block, a central poly­(acrylic acid) (PAA) block, and a hydrophobic poly­(methyl methacrylate) (PMMA) block using atom transfer radical polymerization technique. We examined the self-a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Molecular pharmaceutics 2016-04, Vol.13 (4), p.1413-1429
Hauptverfasser:	Aydin, Omer, Youssef, Ibrahim, Yuksel Durmaz, Yasemin, Tiruchinapally, Gopinath, ElSayed, Mohamed E. H
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Line Cell Line, Tumor Cells, Cultured Humans Hydrogen-Ion Concentration Macrophages - metabolism Male Micelles Prostatic Neoplasms - metabolism Taxoids - administration & dosage Taxoids - adverse effects Taxoids - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!