A comparison of the gut microbiome between long‐term users and non‐users of proton pump inhibitors

Summary Background Proton pump inhibitor (PPI) use is associated with an increased risk of Clostridium difficile infection (CDI), though the mechanism is unclear. PPI induced alterations to the gut microbiome may facilitate the emergence of CDI, though the effects of PPIs on gut microbiota are not w...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2016-05, Vol.43 (9), p.974-984
Hauptverfasser:	Clooney, A. G., Bernstein, C. N, Leslie, W. D., Vagianos, K., Sargent, M., Laserna‐Mendieta, E. J., Claesson, M. J., Targownik, L. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Bacteroidetes - drug effects Clostridium Infections - physiopathology Feces - microbiology Female Firmicutes - drug effects Gastrointestinal Microbiome - drug effects Humans Male Middle Aged Proton Pump Inhibitors - pharmacology Proton Pump Inhibitors - therapeutic use Risk Factors
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