rDEN4 Delta 30, a Live Attenuated Dengue Virus Type 4 Vaccine Candidate, Is Safe, Immunogenic, and Highly Infectious in Healthy Adult Volunteers

Background. The live attenuated dengue virus type 4 (DEN-4) vaccine candidate virus rDEN4 Delta 30 was previously found to be safe and immunogenic at a dose of 10 super(5) plaque-forming units (pfu). Methods. In a follow-up placebo-controlled phase 2 clinical trial, rDEN4 Delta 30 was administered a...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	The Journal of infectious diseases 2005-03, Vol.191 (5), p.710-718
Hauptverfasser:	Durbin, A P, Whitehead, S S, McArthur, J, Perreault, J R, Blaney, JE Jr, Thumar, B, Murphy, B R, Karron, R A
Format:	Artikel
Sprache:	eng
Schlagworte:	Dengue virus type 4
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!