New Cyclodextrin-Bearing 8-Hydroxyquinoline Ligands as Multifunctional Molecules

Recent investigations have rekindled interest in 8‐hydroxyquinolines as therapeutic agents for cancer, Alzheimer’s disease, and other neurodegenerative disorders. Three new β‐cyclodextrin conjugates of 8‐hydroxyquinolines and their copper(II) and zinc(II) complexes have been synthesized and characte...

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Veröffentlicht in:	Chemistry : a European journal 2013-10, Vol.19 (41), p.13946-13955
Hauptverfasser:	Oliveri, Valentina, Puglisi, Antonino, Viale, Maurizio, Aiello, Cinzia, Sgarlata, Carmelo, Vecchio, Graziella, Clarke, James, Milton, John, Spencer, John
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Antioxidants - chemical synthesis Antioxidants - chemistry Antioxidants - metabolism chelating agents Chelating Agents - chemical synthesis Chelating Agents - chemistry Chelating Agents - metabolism Chemical compounds Chemistry Conjugates Coordination Complexes - chemical synthesis Coordination Complexes - chemistry Coordination Complexes - metabolism Copper Copper - chemistry Cyclodextrins Cyclodextrins - chemistry Diseases glycoconjugates Glycoconjugates - chemistry Ligands Metals - chemistry Metals - therapeutic use Oxidative Stress Oxyquinoline - chemistry Pharmacology Solubility Stresses Superoxide Dismutase - chemistry Superoxide Dismutase - metabolism Superoxide Dismutase - therapeutic use zinc Zinc - chemistry
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