Degradability of creatinine under sewer conditions affects its potential to be used as biomarker in sewage epidemiology
Creatinine was proposed to be used as a population normalising factor in sewage epidemiology but its stability in the sewer system has not been assessed. This study thus aimed to evaluate the fate of creatinine under different sewer conditions using laboratory sewer reactors. The results showed that...
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| Veröffentlicht in: | Water research (Oxford) 2014-05, Vol.55, p.272-279 |
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| creator | Thai, Phong K. O'Brien, Jake Jiang, Guangming Gernjak, Wolfgang Yuan, Zhiguo Eaglesham, Geoff Mueller, Jochen F. |
| description | Creatinine was proposed to be used as a population normalising factor in sewage epidemiology but its stability in the sewer system has not been assessed. This study thus aimed to evaluate the fate of creatinine under different sewer conditions using laboratory sewer reactors. The results showed that while creatinine was stable in wastewater only, it degraded quickly in reactors with the presence of sewer biofilms. The degradation followed first order kinetics with significantly higher rate in rising main condition than in gravity sewer condition. Additionally, daily loads of creatinine were determined in wastewater samples collected on Census day from 10 wastewater treatment plants around Australia. The measured loads of creatinine from those samples were much lower than expected and did not correlate with the populations across the sampled treatment plants. The results suggested that creatinine may not be a suitable biomarker for population normalisation purpose in sewage epidemiology, especially in sewer catchment with high percentage of rising mains.
[Display omitted]
•It is the first study to assess the stability of creatinine under sewer conditions.•Sewer biofilms significantly enhanced the degradation of creatinine.•Daily load of creatinine in 10 WWTPs in Australia were measured in Census period.•No correlation between daily load of creatinine and population was found. |
| doi_str_mv | 10.1016/j.watres.2014.02.035 |
| format | Article |
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[Display omitted]
•It is the first study to assess the stability of creatinine under sewer conditions.•Sewer biofilms significantly enhanced the degradation of creatinine.•Daily load of creatinine in 10 WWTPs in Australia were measured in Census period.•No correlation between daily load of creatinine and population was found.</description><identifier>ISSN: 0043-1354</identifier><identifier>EISSN: 1879-2448</identifier><identifier>DOI: 10.1016/j.watres.2014.02.035</identifier><identifier>PMID: 24631876</identifier><identifier>CODEN: WATRAG</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>Air. Soil. Water. Waste. Feeding ; Biological and medical sciences ; Biomarkers ; Bioreactors - microbiology ; Creatinine ; Creatinine - metabolism ; Degradation ; Environment. Living conditions ; Environmental Monitoring - methods ; Epidemiology ; Medical sciences ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Reactors ; Sewage ; Sewage - microbiology ; Sewer biofilms ; Sewer reactor ; Sewers ; Stability ; Waste Disposal, Fluid ; Wastewater analysis ; Wastewater treatment</subject><ispartof>Water research (Oxford), 2014-05, Vol.55, p.272-279</ispartof><rights>2014 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2014 Elsevier Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c458t-5057359bd7f20429cec7742a2e86b07cae3acfa9e64078cb9058450c9a13a57d3</citedby><cites>FETCH-LOGICAL-c458t-5057359bd7f20429cec7742a2e86b07cae3acfa9e64078cb9058450c9a13a57d3</cites><orcidid>0000-0003-0042-3057</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0043135414001511$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28395685$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/24631876$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thai, Phong K.</creatorcontrib><creatorcontrib>O'Brien, Jake</creatorcontrib><creatorcontrib>Jiang, Guangming</creatorcontrib><creatorcontrib>Gernjak, Wolfgang</creatorcontrib><creatorcontrib>Yuan, Zhiguo</creatorcontrib><creatorcontrib>Eaglesham, Geoff</creatorcontrib><creatorcontrib>Mueller, Jochen F.</creatorcontrib><title>Degradability of creatinine under sewer conditions affects its potential to be used as biomarker in sewage epidemiology</title><title>Water research (Oxford)</title><addtitle>Water Res</addtitle><description>Creatinine was proposed to be used as a population normalising factor in sewage epidemiology but its stability in the sewer system has not been assessed. This study thus aimed to evaluate the fate of creatinine under different sewer conditions using laboratory sewer reactors. The results showed that while creatinine was stable in wastewater only, it degraded quickly in reactors with the presence of sewer biofilms. The degradation followed first order kinetics with significantly higher rate in rising main condition than in gravity sewer condition. Additionally, daily loads of creatinine were determined in wastewater samples collected on Census day from 10 wastewater treatment plants around Australia. The measured loads of creatinine from those samples were much lower than expected and did not correlate with the populations across the sampled treatment plants. The results suggested that creatinine may not be a suitable biomarker for population normalisation purpose in sewage epidemiology, especially in sewer catchment with high percentage of rising mains.
[Display omitted]
•It is the first study to assess the stability of creatinine under sewer conditions.•Sewer biofilms significantly enhanced the degradation of creatinine.•Daily load of creatinine in 10 WWTPs in Australia were measured in Census period.•No correlation between daily load of creatinine and population was found.</description><subject>Air. Soil. Water. Waste. Feeding</subject><subject>Biological and medical sciences</subject><subject>Biomarkers</subject><subject>Bioreactors - microbiology</subject><subject>Creatinine</subject><subject>Creatinine - metabolism</subject><subject>Degradation</subject><subject>Environment. Living conditions</subject><subject>Environmental Monitoring - methods</subject><subject>Epidemiology</subject><subject>Medical sciences</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Reactors</subject><subject>Sewage</subject><subject>Sewage - microbiology</subject><subject>Sewer biofilms</subject><subject>Sewer reactor</subject><subject>Sewers</subject><subject>Stability</subject><subject>Waste Disposal, Fluid</subject><subject>Wastewater analysis</subject><subject>Wastewater treatment</subject><issn>0043-1354</issn><issn>1879-2448</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU2vEyEUhonReOvVf2AMGxM3HfkcYGNirp_JTdzomjBwpqFOoQK16b-XplV3xgWwed6XAw9CzykZKKHj6-1wdK1AHRihYiBsIFw-QCuqlVkzIfRDtCJE8DXlUtygJ7VuCSGMcfMY3TAx8g6OK3R8B5vigpviEtsJ5xn7Aq7FFBPgQwpQcIVj331OIbaYU8VunsG3imNf-9wgtegW3DKeeqRCwK7iKeadK997MKZzg9sAhn0MsIt5yZvTU_RodkuFZ9fzFn378P7r3af1_ZePn-_e3q-9kLqtJZGKSzMFNTMimPHglRLMMdDjRJR3wJ2fnYFREKX9ZIjUQhJvHOVOqsBv0atL777kHweoze5i9bAsLkE-VEuV0oQZQdl_oGLUhiijOiouqC-51gKz3ZfY33uylNizHbu1Fzv2bMcSZrudHntxveEw7SD8Cf3W0YGXV8BV75a5uORj_ctpbuSoz0VvLhz0r_sZodjqIyQPIZauxoYc_z3JL1eEsPI</recordid><startdate>20140515</startdate><enddate>20140515</enddate><creator>Thai, Phong K.</creator><creator>O'Brien, Jake</creator><creator>Jiang, Guangming</creator><creator>Gernjak, Wolfgang</creator><creator>Yuan, Zhiguo</creator><creator>Eaglesham, Geoff</creator><creator>Mueller, Jochen F.</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QH</scope><scope>7ST</scope><scope>7UA</scope><scope>C1K</scope><scope>F1W</scope><scope>H97</scope><scope>L.G</scope><scope>SOI</scope><scope>8FD</scope><scope>FR3</scope><scope>KR7</scope><orcidid>https://orcid.org/0000-0003-0042-3057</orcidid></search><sort><creationdate>20140515</creationdate><title>Degradability of creatinine under sewer conditions affects its potential to be used as biomarker in sewage epidemiology</title><author>Thai, Phong K. ; O'Brien, Jake ; Jiang, Guangming ; Gernjak, Wolfgang ; Yuan, Zhiguo ; Eaglesham, Geoff ; Mueller, Jochen F.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c458t-5057359bd7f20429cec7742a2e86b07cae3acfa9e64078cb9058450c9a13a57d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>Air. Soil. Water. Waste. Feeding</topic><topic>Biological and medical sciences</topic><topic>Biomarkers</topic><topic>Bioreactors - microbiology</topic><topic>Creatinine</topic><topic>Creatinine - metabolism</topic><topic>Degradation</topic><topic>Environment. Living conditions</topic><topic>Environmental Monitoring - methods</topic><topic>Epidemiology</topic><topic>Medical sciences</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Reactors</topic><topic>Sewage</topic><topic>Sewage - microbiology</topic><topic>Sewer biofilms</topic><topic>Sewer reactor</topic><topic>Sewers</topic><topic>Stability</topic><topic>Waste Disposal, Fluid</topic><topic>Wastewater analysis</topic><topic>Wastewater treatment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thai, Phong K.</creatorcontrib><creatorcontrib>O'Brien, Jake</creatorcontrib><creatorcontrib>Jiang, Guangming</creatorcontrib><creatorcontrib>Gernjak, Wolfgang</creatorcontrib><creatorcontrib>Yuan, Zhiguo</creatorcontrib><creatorcontrib>Eaglesham, Geoff</creatorcontrib><creatorcontrib>Mueller, Jochen F.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aqualine</collection><collection>Environment Abstracts</collection><collection>Water Resources Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Environment Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Civil Engineering Abstracts</collection><jtitle>Water research (Oxford)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thai, Phong K.</au><au>O'Brien, Jake</au><au>Jiang, Guangming</au><au>Gernjak, Wolfgang</au><au>Yuan, Zhiguo</au><au>Eaglesham, Geoff</au><au>Mueller, Jochen F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Degradability of creatinine under sewer conditions affects its potential to be used as biomarker in sewage epidemiology</atitle><jtitle>Water research (Oxford)</jtitle><addtitle>Water Res</addtitle><date>2014-05-15</date><risdate>2014</risdate><volume>55</volume><spage>272</spage><epage>279</epage><pages>272-279</pages><issn>0043-1354</issn><eissn>1879-2448</eissn><coden>WATRAG</coden><abstract>Creatinine was proposed to be used as a population normalising factor in sewage epidemiology but its stability in the sewer system has not been assessed. This study thus aimed to evaluate the fate of creatinine under different sewer conditions using laboratory sewer reactors. The results showed that while creatinine was stable in wastewater only, it degraded quickly in reactors with the presence of sewer biofilms. The degradation followed first order kinetics with significantly higher rate in rising main condition than in gravity sewer condition. Additionally, daily loads of creatinine were determined in wastewater samples collected on Census day from 10 wastewater treatment plants around Australia. The measured loads of creatinine from those samples were much lower than expected and did not correlate with the populations across the sampled treatment plants. The results suggested that creatinine may not be a suitable biomarker for population normalisation purpose in sewage epidemiology, especially in sewer catchment with high percentage of rising mains.
[Display omitted]
•It is the first study to assess the stability of creatinine under sewer conditions.•Sewer biofilms significantly enhanced the degradation of creatinine.•Daily load of creatinine in 10 WWTPs in Australia were measured in Census period.•No correlation between daily load of creatinine and population was found.</abstract><cop>Kidlington</cop><pub>Elsevier Ltd</pub><pmid>24631876</pmid><doi>10.1016/j.watres.2014.02.035</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0003-0042-3057</orcidid></addata></record> |
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| subjects | Air. Soil. Water. Waste. Feeding Biological and medical sciences Biomarkers Bioreactors - microbiology Creatinine Creatinine - metabolism Degradation Environment. Living conditions Environmental Monitoring - methods Epidemiology Medical sciences Public health. Hygiene Public health. Hygiene-occupational medicine Reactors Sewage Sewage - microbiology Sewer biofilms Sewer reactor Sewers Stability Waste Disposal, Fluid Wastewater analysis Wastewater treatment |
| title | Degradability of creatinine under sewer conditions affects its potential to be used as biomarker in sewage epidemiology |
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