Targeted Tumor Computed Tomography Imaging Using Low-Generation Dendrimer-Stabilized Gold Nanoparticles

We report a facile approach to fabricating low‐generation poly(amidoamine) (PAMAM) dendrimer‐stabilized gold nanoparticles (Au DSNPs) functionalized with folic acid (FA) for in vitro and in vivo targeted computed tomography (CT) imaging of cancer cells. In this study, amine‐terminated generation 2 P...

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Veröffentlicht in:	Chemistry : a European journal 2013-05, Vol.19 (20), p.6409-6416
Hauptverfasser:	Liu, Hui, Xu, Yanhong, Wen, Shihui, Chen, Qian, Zheng, Linfeng, Shen, Mingwu, Zhao, Jinglong, Zhang, Guixiang, Shi, Xiangyang
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Cancer cancer cells Chemistry Contrast agents Contrast Media - chemistry dendrimers Dendrimers - chemistry Folic Acid - chemistry Gold Gold - chemistry Humans Imaging imaging agents In vitro testing In vivo testing KB Cells Metal Nanoparticles - chemistry Nanoparticles Neoplasms - diagnosis Neoplasms - diagnostic imaging Neoplasms - pathology synthesis Tomography, X-Ray Computed - methods X-Rays
Online-Zugang:	Volltext
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