Dynamic Self-Assembly of Polycationic Clusters Based on Cyclodextrins for pH-Sensitive DNA Nanocondensation and Delivery by Component Design

The ability of cyclodextrin‐based polycationic cluster to undergo reversible DNA condensation and release in a physiologically useful pH window has been finely tuned by the installation of a capping xylylene moiety at the secondary face of the cyclooligosaccharide. This strategy can be exploited adv...

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Veröffentlicht in:Chemistry : a European journal 2014-05, Vol.20 (22), p.6622-6627
Hauptverfasser: Gallego-Yerga, Laura, González-Álvarez, M. José, Mayordomo, Natalia, Santoyo-González, Francisco, Benito, Juan M., Ortiz Mellet, Carmen, Mendicuti, Francisco, García Fernández, José M.
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Sprache:eng
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