Association of BRAF V600E Mutation and MicroRNA Expression with Central Lymph Node Metastases in Papillary Thyroid Cancer: A Prospective Study from Four Endocrine Surgery Centers

Studies have demonstrated an association of the BRAF(V600E) mutation and microRNA (miR) expression with aggressive clinicopathologic features in papillary thyroid cancer (PTC). Analysis of BRAF(V600E) mutations with miR expression data may improve perioperative decision making for patients with PTC,...

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Veröffentlicht in:	Thyroid (New York, N.Y.) N.Y.), 2016-04, Vol.26 (4), p.532-542
Hauptverfasser:	Han, Patricia Aragon, Kim, Hyun-seok, Cho, Soonweng, Fazeli, Roghayeh, Najafian, Alireza, Khawaja, Hunain, McAlexander, Melissa, Dy, Benzon, Sorensen, Meredith, Aronova, Anna, Sebo, Thomas J, Giordano, Thomas J, Fahey, 3rd, Thomas J, Thompson, Geoffrey B, Gauger, Paul G, Somervell, Helina, Bishop, Justin A, Eshleman, James R, Schneider, Eric B, Witwer, Kenneth W, Umbricht, Christopher B, Zeiger, Martha A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers, Tumor - genetics Carcinoma - genetics Carcinoma - pathology Carcinoma, Papillary - pathology Decision Making Female Humans Lymph Node Excision Lymphatic Metastasis Male MicroRNAs - genetics MicroRNAs - metabolism Middle Aged Multivariate Analysis Mutation Prognosis Prospective Studies Proto-Oncogene Proteins B-raf - genetics Thyroid Cancer, Papillary Thyroid Neoplasms - genetics Thyroid Neoplasms - pathology Thyroidectomy - methods
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