The effect of adjuvant remifentanil with propofol or thiopentone on seizure quality during electroconvulsive therapy
In order to optimise outcome to electroconvulsive therapy (ECT), there has been a trend to remifentanil as an adjunct to standard intravenous induction agents. This has allowed a reduction in the dose of anaesthetic agent, and usually an improved response to stimulation. However there have been no p...
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| Veröffentlicht in: | Anaesthesia and intensive care 2016-03, Vol.44 (2), p.278-280 |
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| creator | MacPherson, R Marroquin-Harris, M Gálvez, V Tor, P Loo, C |
| description | In order to optimise outcome to electroconvulsive therapy (ECT), there has been a trend to remifentanil as an adjunct to standard intravenous induction agents. This has allowed a reduction in the dose of anaesthetic agent, and usually an improved response to stimulation. However there have been no previous studies to ascertain whether this improvement is simply as a result of the reduced dose of anaesthetic agent or whether remifentanil itself might possess epileptogenic properties. This retrospective case-controlled study examined ECT outcomes, determined by electroencephalography (EEG) quality analysis, in patients who received ECT with or without remifentanil, where there was no dose reduction in the anaesthetic agent. There were no improvements seen in the measurements of any EEG parameter, including seizure duration. These observations suggest that remifentanil does not possess any intrinsic proconvulsant activity and that any improvement in outcome seen with its use is as a result of dose reduction in the IV anaesthetic agent. |
| doi_str_mv | 10.1177/0310057X1604400215 |
| format | Article |
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This has allowed a reduction in the dose of anaesthetic agent, and usually an improved response to stimulation. However there have been no previous studies to ascertain whether this improvement is simply as a result of the reduced dose of anaesthetic agent or whether remifentanil itself might possess epileptogenic properties. This retrospective case-controlled study examined ECT outcomes, determined by electroencephalography (EEG) quality analysis, in patients who received ECT with or without remifentanil, where there was no dose reduction in the anaesthetic agent. There were no improvements seen in the measurements of any EEG parameter, including seizure duration. 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Marroquin-Harris, M ; Gálvez, V ; Tor, P ; Loo, C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c496t-9577a2be074cddb01f526f6b564fe3b06733b627d5438719169efefa05eb76d53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Administration</topic><topic>Adult</topic><topic>Aged</topic><topic>Anesthetics</topic><topic>Case-Control Studies</topic><topic>Complications</topic><topic>Data processing</topic><topic>Electroconvulsive Therapy</topic><topic>Electroencephalography - drug effects</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Patient monitoring</topic><topic>Piperidines - administration & dosage</topic><topic>Propofol - administration & dosage</topic><topic>Remifentanil</topic><topic>Retrospective Studies</topic><topic>Seizures - therapy</topic><topic>Thiopental - administration & dosage</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MacPherson, R</creatorcontrib><creatorcontrib>Marroquin-Harris, M</creatorcontrib><creatorcontrib>Gálvez, V</creatorcontrib><creatorcontrib>Tor, P</creatorcontrib><creatorcontrib>Loo, C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>University Readers</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Australia & New Zealand Database</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>Anaesthesia and intensive care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MacPherson, R</au><au>Marroquin-Harris, M</au><au>Gálvez, V</au><au>Tor, P</au><au>Loo, C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of adjuvant remifentanil with propofol or thiopentone on seizure quality during electroconvulsive therapy</atitle><jtitle>Anaesthesia and intensive care</jtitle><addtitle>Anaesth Intensive Care</addtitle><date>2016-03-01</date><risdate>2016</risdate><volume>44</volume><issue>2</issue><spage>278</spage><epage>280</epage><pages>278-280</pages><issn>0310-057X</issn><eissn>1448-0271</eissn><abstract>In order to optimise outcome to electroconvulsive therapy (ECT), there has been a trend to remifentanil as an adjunct to standard intravenous induction agents. 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| ispartof | Anaesthesia and intensive care, 2016-03, Vol.44 (2), p.278-280 |
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| source | MEDLINE; SAGE Complete; Alma/SFX Local Collection |
| subjects | Administration Adult Aged Anesthetics Case-Control Studies Complications Data processing Electroconvulsive Therapy Electroencephalography - drug effects Female Humans Male Middle Aged Patient monitoring Piperidines - administration & dosage Propofol - administration & dosage Remifentanil Retrospective Studies Seizures - therapy Thiopental - administration & dosage |
| title | The effect of adjuvant remifentanil with propofol or thiopentone on seizure quality during electroconvulsive therapy |
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