Pressure algometry and enzyme-linked immunosorbent assay of natural antibodies in the evaluation of pain syndrome
The dynamics of possible markers of pain syndrome: pain pressure thresholds of intolerance (PTI) and natural antibodies to mediators of pain processing (nAbs) in blood serum at dorsalgia was studied. We have shown that most men and women had reduced PTIs. Night PTIs were lower than daytime PTIs rega...
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| Veröffentlicht in: | Doklady. Biochemistry and biophysics 2016, Vol.466 (1), p.43-46 |
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| container_title | Doklady. Biochemistry and biophysics |
| container_volume | 466 |
| creator | Levashova, A. I. Artiushkova, O. Yu Morozova, V. S. Petrochenko, S. N. Myagkova, M. A. Moseikin, I. A. Panchenko, L. F. |
| description | The dynamics of possible markers of pain syndrome: pain pressure thresholds of intolerance (PTI) and natural antibodies to mediators of pain processing (nAbs) in blood serum at dorsalgia was studied. We have shown that most men and women had reduced PTIs. Night PTIs were lower than daytime PTIs regardless of the gender. The study of the content of nAbs to opioids and biogenic amines by ELISA have shown a prolonged maintenance of their elevated and high levels that could evoke long-term effect in pain chronization. Thus, the pressure algometry and ELISA of nAbs to pain processing mediators make it possible to assess the individual pain status objectively and, on this bases, to propose personal schemes of treatment. |
| doi_str_mv | 10.1134/S1607672916010129 |
| format | Article |
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Biochemistry and biophysics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Levashova, A. I.</au><au>Artiushkova, O. Yu</au><au>Morozova, V. S.</au><au>Petrochenko, S. N.</au><au>Myagkova, M. A.</au><au>Moseikin, I. A.</au><au>Panchenko, L. F.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pressure algometry and enzyme-linked immunosorbent assay of natural antibodies in the evaluation of pain syndrome</atitle><jtitle>Doklady. Biochemistry and biophysics</jtitle><stitle>Dokl Biochem Biophys</stitle><addtitle>Dokl Biochem Biophys</addtitle><date>2016</date><risdate>2016</risdate><volume>466</volume><issue>1</issue><spage>43</spage><epage>46</epage><pages>43-46</pages><issn>1607-6729</issn><eissn>1608-3091</eissn><abstract>The dynamics of possible markers of pain syndrome: pain pressure thresholds of intolerance (PTI) and natural antibodies to mediators of pain processing (nAbs) in blood serum at dorsalgia was studied. We have shown that most men and women had reduced PTIs. Night PTIs were lower than daytime PTIs regardless of the gender. The study of the content of nAbs to opioids and biogenic amines by ELISA have shown a prolonged maintenance of their elevated and high levels that could evoke long-term effect in pain chronization. Thus, the pressure algometry and ELISA of nAbs to pain processing mediators make it possible to assess the individual pain status objectively and, on this bases, to propose personal schemes of treatment.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><pmid>27025486</pmid><doi>10.1134/S1607672916010129</doi><tpages>4</tpages></addata></record> |
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| identifier | ISSN: 1607-6729 |
| ispartof | Doklady. Biochemistry and biophysics, 2016, Vol.466 (1), p.43-46 |
| issn | 1607-6729 1608-3091 |
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| subjects | Adolescent Adult Aged Antibodies - immunology Biochemistry Biological and Medical Physics Biomarkers - blood Biomedical and Life Sciences Biophysics Biophysics and Molecular Biology Enzyme-Linked Immunosorbent Assay Enzymes Female Humans Immunoassay Life Sciences Male Middle Aged Pain Pain management Pain Measurement - methods Pain Threshold Pressure Sciatica - blood Sciatica - diagnosis Touch |
| title | Pressure algometry and enzyme-linked immunosorbent assay of natural antibodies in the evaluation of pain syndrome |
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