Empirical tuberculosis therapy versus isoniazid in adult outpatients with advanced HIV initiating antiretroviral therapy (REMEMBER): a multicountry open-label randomised controlled trial

Summary Background Mortality within the first 6 months after initiating antiretroviral therapy is common in resource-limited settings and is often due to tuberculosis in patients with advanced HIV disease. Isoniazid preventive therapy is recommended in HIV-positive adults, but subclinical tuberculos...

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Veröffentlicht in:	The Lancet (British edition) 2016-03, Vol.387 (10024), p.1198-1209
Hauptverfasser:	Hosseinipour, Mina C, Prof, Bisson, Gregory P, MD, Miyahara, Sachiko, PhD, Sun, Xin, MS, Moses, Agnes, MMED, Riviere, Cynthia, MD, Kirui, Fredrick K, MMED, Badal-Faesen, Sharlaa, MBBCh, Lagat, David, MBChB, Nyirenda, Mulinda, MMED, Naidoo, Kogieleum, MBChB, Hakim, James, Prof, Mugyenyi, Peter, Prof, Henostroza, German, MD, Leger, Paul D, MD, Lama, Javier R, MD, Mohapi, Lerato, MBBCh, Alave, Jorge, MD, Mave, Vidya, MD, Veloso, Valdilea G, MD, Pillay, Sandy, MBChB, Kumarasamy, Nagalingeswaran, PhD, Bao, Jing, MD, Hogg, Evelyn, BA, Jones, Lynne, MT ASCP, Zolopa, Andrew, Prof, Kumwenda, Johnstone, Prof, Gupta, Amita, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS-Related Opportunistic Infections - immunology AIDS-Related Opportunistic Infections - prevention & control Allergies Ambulatory Care Facilities Anti-HIV Agents - therapeutic use Antiretroviral agents Antiretroviral drugs Antitubercular Agents - therapeutic use CD4 Lymphocyte Count Clinical trials Drug therapy Female HIV HIV Infections - drug therapy HIV Infections - immunology Human immunodeficiency virus Humans Infectious diseases Internal Medicine Isoniazid - therapeutic use Kaplan-Meier Estimate Male Mortality Mycobacterium Preventive medicine Treatment Outcome Tuberculosis Tuberculosis - immunology Tuberculosis - prevention & control
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