Eribulin upregulates miR-195 expression and downregulates Wnt3a expression in non-basal-like type of triple-negative breast cancer cell MDA-MB-231

Triple-negative breast cancer (TNBC), which does not show hormone sensitivity, is a poor prognosis disease without an established targeted treatment, so that establishing a therapeutic target for each subtype is desired. In addition, microRNA (miRNA), a non-cording RNA 19–25 nucleotide-longs in leng...

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Veröffentlicht in:	Human cell : official journal of Human Cell Research Society 2016-04, Vol.29 (2), p.76-82
Hauptverfasser:	Furuya, Kanji, Sasaki, Akiko, Tsunoda, Yuko, Tsuji, Mayumi, Udaka, Yuko, Oyamada, Hideto, Tsuchiya, Hiromichi, Oguchi, Katsuji
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomedical and Life Sciences Breast Neoplasms - genetics Breast Neoplasms - pathology Cell Biology Cell Line, Tumor Down-Regulation - drug effects Female Furans - pharmacology Furans - therapeutic use Gene Expression - drug effects Genes, Tumor Suppressor Gynecology Humans Ketones - pharmacology Ketones - therapeutic use Life Sciences MicroRNAs - genetics MicroRNAs - metabolism MicroRNAs - physiology Molecular Targeted Therapy Oncology Reproductive Medicine Research Article Signal Transduction - genetics Signal Transduction - physiology Stem Cells Surgery Up-Regulation - drug effects Wnt3A Protein - genetics Wnt3A Protein - metabolism
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