Use of the Montreal Cognitive Assessment and Alzheimer's Disease-8 as cognitive screening measures in Parkinson's disease
Objective To examine the sensitivity and specificity of the Montreal Cognitive Assessment (MoCA), a brief cognitive screening measure previously validated for use in Parkinson's disease (PD), and Alzheimer's Disease‐8 (AD8), an eight‐item informant report used to screen for dementia, but n...
Gespeichert in:
| Veröffentlicht in: | International journal of geriatric psychiatry 2016-03, Vol.31 (3), p.264-272 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 272 |
|---|---|
| container_issue | 3 |
| container_start_page | 264 |
| container_title | International journal of geriatric psychiatry |
| container_volume | 31 |
| creator | Brown, Daniel S. Bernstein, Ira H. McClintock, Shawn M. Munro Cullum, C. Dewey Jr, Richard B. Husain, Mustafa Lacritz, Laura H. |
| description | Objective
To examine the sensitivity and specificity of the Montreal Cognitive Assessment (MoCA), a brief cognitive screening measure previously validated for use in Parkinson's disease (PD), and Alzheimer's Disease‐8 (AD8), an eight‐item informant report used to screen for dementia, but not yet validated for use in PD, to identify cognitive impairment in a sample of 111 patients with PD.
Methods
Cognitive impairment was determined based on a battery of neuropsychological measures, excluding the MoCA and AD8. Classification rates of both the MoCA and AD8 in identifying cognitive impairment were examined using logistic regression and receiver operator characteristic (ROC) analysis. Optimal cutoff scores were determined to maximize sensitivity and specificity.
Results
The MoCA correctly classified 78.4% of participants (p |
| doi_str_mv | 10.1002/gps.4320 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1776665572</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1765579935</sourcerecordid><originalsourceid>FETCH-LOGICAL-c5200-262e93c7f29cbaa868b104ccc3277c43b77a901263476dbf62650d3c49c827053</originalsourceid><addsrcrecordid>eNqNkU2P0zAQhiMEYsuCxC9AljjAJYs_Yjs-dgtbkHZhpbLiaDnOpOslcYonAcqvJ6WlSEhInOYwz_tIM2-WPWX0jFHKX603eFYITu9lM0aNyRlT6n42o2Upc8UFPckeId5ROu1Y-TA74YpprZmcZdsbBNI3ZLgFctXHIYFryaJfxzCEr0DmiIDYQRyIizWZtz9uIXSQXiB5HRAcQl4Sh8QfE-gTQAxxTbppPSZAEiK5dulziNjHKVjvg4-zB41rEZ4c5ml2c_Hm4-Jtfvlh-W4xv8y95JTmXHEwwuuGG185V6qyYrTw3guutS9EpbUzlHElCq3qqlFcSVoLXxhfck2lOM1e7r2b1H8ZAQfbBfTQti5CP6KdPqGUklLz_0B3nDFiZ33-F3rXjylOh_yiRCELaf4IfeoREzR2k0Ln0tYyanfN2ak5u2tuQp8dhGPVQX0Ef1c1Afke-BZa2P5TZJfXq4PwwAcc4PuRn4qwSgst7af3S7syVxf8fCUsEz8BhqSvkQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1765345459</pqid></control><display><type>article</type><title>Use of the Montreal Cognitive Assessment and Alzheimer's Disease-8 as cognitive screening measures in Parkinson's disease</title><source>MEDLINE</source><source>Wiley Journals</source><creator>Brown, Daniel S. ; Bernstein, Ira H. ; McClintock, Shawn M. ; Munro Cullum, C. ; Dewey Jr, Richard B. ; Husain, Mustafa ; Lacritz, Laura H.</creator><creatorcontrib>Brown, Daniel S. ; Bernstein, Ira H. ; McClintock, Shawn M. ; Munro Cullum, C. ; Dewey Jr, Richard B. ; Husain, Mustafa ; Lacritz, Laura H.</creatorcontrib><description>Objective
To examine the sensitivity and specificity of the Montreal Cognitive Assessment (MoCA), a brief cognitive screening measure previously validated for use in Parkinson's disease (PD), and Alzheimer's Disease‐8 (AD8), an eight‐item informant report used to screen for dementia, but not yet validated for use in PD, to identify cognitive impairment in a sample of 111 patients with PD.
Methods
Cognitive impairment was determined based on a battery of neuropsychological measures, excluding the MoCA and AD8. Classification rates of both the MoCA and AD8 in identifying cognitive impairment were examined using logistic regression and receiver operator characteristic (ROC) analysis. Optimal cutoff scores were determined to maximize sensitivity and specificity.
Results
The MoCA correctly classified 78.4% of participants (p < 0.001), and ROC analysis yielded an area under the curve (AUC) of 0.82. A MoCA cutoff score of <25 yielded optimal sensitivity (0.77) and specificity (0.79) for identifying PD patients with cognitive impairment. Similar analyses for the AD8 were statistically nonsignificant, although the classification rate was 70.5%, with an AUC of 0.50.
Conclusions
These results provide additional support for the MoCA, but not the AD8, in identifying cognitive impairment in patients with PD. Copyright @ 2015 John Wiley & Sons, Ltd.</description><identifier>ISSN: 0885-6230</identifier><identifier>EISSN: 1099-1166</identifier><identifier>DOI: 10.1002/gps.4320</identifier><identifier>PMID: 26177715</identifier><identifier>CODEN: IJGPES</identifier><language>eng</language><publisher>England: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Alzheimer's disease ; Alzheimer's Disease-8 ; Brief Psychiatric Rating Scale - standards ; brief screening measures ; Cognition Disorders - diagnosis ; Cognitive ability ; cognitive impairment ; Female ; Geriatric psychiatry ; Geriatric psychology ; Humans ; Logistic Models ; Male ; Middle Aged ; Montreal Cognitive Assessment ; neuropsychological assessment ; Neuropsychological Tests - standards ; Parkinson Disease - diagnosis ; Parkinson's disease ; ROC Curve ; Sensitivity and Specificity</subject><ispartof>International journal of geriatric psychiatry, 2016-03, Vol.31 (3), p.264-272</ispartof><rights>Copyright © 2015 John Wiley & Sons, Ltd.</rights><rights>Copyright © 2016 John Wiley & Sons, Ltd.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c5200-262e93c7f29cbaa868b104ccc3277c43b77a901263476dbf62650d3c49c827053</citedby><cites>FETCH-LOGICAL-c5200-262e93c7f29cbaa868b104ccc3277c43b77a901263476dbf62650d3c49c827053</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fgps.4320$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fgps.4320$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26177715$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Brown, Daniel S.</creatorcontrib><creatorcontrib>Bernstein, Ira H.</creatorcontrib><creatorcontrib>McClintock, Shawn M.</creatorcontrib><creatorcontrib>Munro Cullum, C.</creatorcontrib><creatorcontrib>Dewey Jr, Richard B.</creatorcontrib><creatorcontrib>Husain, Mustafa</creatorcontrib><creatorcontrib>Lacritz, Laura H.</creatorcontrib><title>Use of the Montreal Cognitive Assessment and Alzheimer's Disease-8 as cognitive screening measures in Parkinson's disease</title><title>International journal of geriatric psychiatry</title><addtitle>Int J Geriatr Psychiatry</addtitle><description>Objective
To examine the sensitivity and specificity of the Montreal Cognitive Assessment (MoCA), a brief cognitive screening measure previously validated for use in Parkinson's disease (PD), and Alzheimer's Disease‐8 (AD8), an eight‐item informant report used to screen for dementia, but not yet validated for use in PD, to identify cognitive impairment in a sample of 111 patients with PD.
Methods
Cognitive impairment was determined based on a battery of neuropsychological measures, excluding the MoCA and AD8. Classification rates of both the MoCA and AD8 in identifying cognitive impairment were examined using logistic regression and receiver operator characteristic (ROC) analysis. Optimal cutoff scores were determined to maximize sensitivity and specificity.
Results
The MoCA correctly classified 78.4% of participants (p < 0.001), and ROC analysis yielded an area under the curve (AUC) of 0.82. A MoCA cutoff score of <25 yielded optimal sensitivity (0.77) and specificity (0.79) for identifying PD patients with cognitive impairment. Similar analyses for the AD8 were statistically nonsignificant, although the classification rate was 70.5%, with an AUC of 0.50.
Conclusions
These results provide additional support for the MoCA, but not the AD8, in identifying cognitive impairment in patients with PD. Copyright @ 2015 John Wiley & Sons, Ltd.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Alzheimer's disease</subject><subject>Alzheimer's Disease-8</subject><subject>Brief Psychiatric Rating Scale - standards</subject><subject>brief screening measures</subject><subject>Cognition Disorders - diagnosis</subject><subject>Cognitive ability</subject><subject>cognitive impairment</subject><subject>Female</subject><subject>Geriatric psychiatry</subject><subject>Geriatric psychology</subject><subject>Humans</subject><subject>Logistic Models</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Montreal Cognitive Assessment</subject><subject>neuropsychological assessment</subject><subject>Neuropsychological Tests - standards</subject><subject>Parkinson Disease - diagnosis</subject><subject>Parkinson's disease</subject><subject>ROC Curve</subject><subject>Sensitivity and Specificity</subject><issn>0885-6230</issn><issn>1099-1166</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU2P0zAQhiMEYsuCxC9AljjAJYs_Yjs-dgtbkHZhpbLiaDnOpOslcYonAcqvJ6WlSEhInOYwz_tIM2-WPWX0jFHKX603eFYITu9lM0aNyRlT6n42o2Upc8UFPckeId5ROu1Y-TA74YpprZmcZdsbBNI3ZLgFctXHIYFryaJfxzCEr0DmiIDYQRyIizWZtz9uIXSQXiB5HRAcQl4Sh8QfE-gTQAxxTbppPSZAEiK5dulziNjHKVjvg4-zB41rEZ4c5ml2c_Hm4-Jtfvlh-W4xv8y95JTmXHEwwuuGG185V6qyYrTw3guutS9EpbUzlHElCq3qqlFcSVoLXxhfck2lOM1e7r2b1H8ZAQfbBfTQti5CP6KdPqGUklLz_0B3nDFiZ33-F3rXjylOh_yiRCELaf4IfeoREzR2k0Ln0tYyanfN2ak5u2tuQp8dhGPVQX0Ef1c1Afke-BZa2P5TZJfXq4PwwAcc4PuRn4qwSgst7af3S7syVxf8fCUsEz8BhqSvkQ</recordid><startdate>201603</startdate><enddate>201603</enddate><creator>Brown, Daniel S.</creator><creator>Bernstein, Ira H.</creator><creator>McClintock, Shawn M.</creator><creator>Munro Cullum, C.</creator><creator>Dewey Jr, Richard B.</creator><creator>Husain, Mustafa</creator><creator>Lacritz, Laura H.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>201603</creationdate><title>Use of the Montreal Cognitive Assessment and Alzheimer's Disease-8 as cognitive screening measures in Parkinson's disease</title><author>Brown, Daniel S. ; Bernstein, Ira H. ; McClintock, Shawn M. ; Munro Cullum, C. ; Dewey Jr, Richard B. ; Husain, Mustafa ; Lacritz, Laura H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5200-262e93c7f29cbaa868b104ccc3277c43b77a901263476dbf62650d3c49c827053</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Alzheimer's disease</topic><topic>Alzheimer's Disease-8</topic><topic>Brief Psychiatric Rating Scale - standards</topic><topic>brief screening measures</topic><topic>Cognition Disorders - diagnosis</topic><topic>Cognitive ability</topic><topic>cognitive impairment</topic><topic>Female</topic><topic>Geriatric psychiatry</topic><topic>Geriatric psychology</topic><topic>Humans</topic><topic>Logistic Models</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Montreal Cognitive Assessment</topic><topic>neuropsychological assessment</topic><topic>Neuropsychological Tests - standards</topic><topic>Parkinson Disease - diagnosis</topic><topic>Parkinson's disease</topic><topic>ROC Curve</topic><topic>Sensitivity and Specificity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Brown, Daniel S.</creatorcontrib><creatorcontrib>Bernstein, Ira H.</creatorcontrib><creatorcontrib>McClintock, Shawn M.</creatorcontrib><creatorcontrib>Munro Cullum, C.</creatorcontrib><creatorcontrib>Dewey Jr, Richard B.</creatorcontrib><creatorcontrib>Husain, Mustafa</creatorcontrib><creatorcontrib>Lacritz, Laura H.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>International journal of geriatric psychiatry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Brown, Daniel S.</au><au>Bernstein, Ira H.</au><au>McClintock, Shawn M.</au><au>Munro Cullum, C.</au><au>Dewey Jr, Richard B.</au><au>Husain, Mustafa</au><au>Lacritz, Laura H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Use of the Montreal Cognitive Assessment and Alzheimer's Disease-8 as cognitive screening measures in Parkinson's disease</atitle><jtitle>International journal of geriatric psychiatry</jtitle><addtitle>Int J Geriatr Psychiatry</addtitle><date>2016-03</date><risdate>2016</risdate><volume>31</volume><issue>3</issue><spage>264</spage><epage>272</epage><pages>264-272</pages><issn>0885-6230</issn><eissn>1099-1166</eissn><coden>IJGPES</coden><abstract>Objective
To examine the sensitivity and specificity of the Montreal Cognitive Assessment (MoCA), a brief cognitive screening measure previously validated for use in Parkinson's disease (PD), and Alzheimer's Disease‐8 (AD8), an eight‐item informant report used to screen for dementia, but not yet validated for use in PD, to identify cognitive impairment in a sample of 111 patients with PD.
Methods
Cognitive impairment was determined based on a battery of neuropsychological measures, excluding the MoCA and AD8. Classification rates of both the MoCA and AD8 in identifying cognitive impairment were examined using logistic regression and receiver operator characteristic (ROC) analysis. Optimal cutoff scores were determined to maximize sensitivity and specificity.
Results
The MoCA correctly classified 78.4% of participants (p < 0.001), and ROC analysis yielded an area under the curve (AUC) of 0.82. A MoCA cutoff score of <25 yielded optimal sensitivity (0.77) and specificity (0.79) for identifying PD patients with cognitive impairment. Similar analyses for the AD8 were statistically nonsignificant, although the classification rate was 70.5%, with an AUC of 0.50.
Conclusions
These results provide additional support for the MoCA, but not the AD8, in identifying cognitive impairment in patients with PD. Copyright @ 2015 John Wiley & Sons, Ltd.</abstract><cop>England</cop><pub>Blackwell Publishing Ltd</pub><pmid>26177715</pmid><doi>10.1002/gps.4320</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0885-6230 |
| ispartof | International journal of geriatric psychiatry, 2016-03, Vol.31 (3), p.264-272 |
| issn | 0885-6230 1099-1166 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1776665572 |
| source | MEDLINE; Wiley Journals |
| subjects | Adult Aged Aged, 80 and over Alzheimer's disease Alzheimer's Disease-8 Brief Psychiatric Rating Scale - standards brief screening measures Cognition Disorders - diagnosis Cognitive ability cognitive impairment Female Geriatric psychiatry Geriatric psychology Humans Logistic Models Male Middle Aged Montreal Cognitive Assessment neuropsychological assessment Neuropsychological Tests - standards Parkinson Disease - diagnosis Parkinson's disease ROC Curve Sensitivity and Specificity |
| title | Use of the Montreal Cognitive Assessment and Alzheimer's Disease-8 as cognitive screening measures in Parkinson's disease |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-28T03%3A54%3A21IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Use%20of%20the%20Montreal%20Cognitive%20Assessment%20and%20Alzheimer's%20Disease-8%20as%20cognitive%20screening%20measures%20in%20Parkinson's%20disease&rft.jtitle=International%20journal%20of%20geriatric%20psychiatry&rft.au=Brown,%20Daniel%20S.&rft.date=2016-03&rft.volume=31&rft.issue=3&rft.spage=264&rft.epage=272&rft.pages=264-272&rft.issn=0885-6230&rft.eissn=1099-1166&rft.coden=IJGPES&rft_id=info:doi/10.1002/gps.4320&rft_dat=%3Cproquest_cross%3E1765579935%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1765345459&rft_id=info:pmid/26177715&rfr_iscdi=true |