Mechanisms of immune escape in central nervous system infection with neurotropic JC virus variant

Objective Symptomatic infections of the central nervous system (CNS) with JC polyomavirus (JCV) usually occur as a result of immunocompromise and manifest as progressive multifocal leukoencephalopathy (PML) or granule cell neuronopathy (GCN). After immune reconstitution, some of these cases may show...

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Veröffentlicht in:	Annals of neurology 2016-03, Vol.79 (3), p.404-418
Hauptverfasser:	Jelcic, Ivan, Jelcic, Ilijas, Kempf, Christian, Largey, Fabienne, Planas, Raquel, Schippling, Sven, Budka, Herbert, Sospedra, Mireia, Martin, Roland
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brain - immunology Brain - virology Female Humans Immune Evasion - immunology Immune Reconstitution Inflammatory Syndrome - immunology Immune Reconstitution Inflammatory Syndrome - virology JC virus JC Virus - classification JC Virus - genetics JC Virus - physiology Leukoencephalopathy, Progressive Multifocal - immunology Leukoencephalopathy, Progressive Multifocal - virology Male Middle Aged Multiple Sclerosis - immunology Multiple Sclerosis - virology Polyomavirus
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