Transforming growth factor- beta adaptor, beta 2-spectrin, modulates cyclin dependent kinase 4 to reduce development of hepatocellular cancer
Transforming growth factor beta (TGF- beta ) is an important regulator of cell growth, and loss of TGF- beta signaling is a hallmark of carcinogenesis. The Smad3/4 adaptor protein beta 2-spectrin ( beta 2SP) is emerging as a potent regulator of tumorigenesis through its ability to modulate the tumor...
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Veröffentlicht in: | Hepatology (Baltimore, Md.) Md.), 2011-05, Vol.53 (5), p.1676-1684 |
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Hauptverfasser: | , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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