A New Na super(+)-Dependent RNA-Cleaving DNAzyme with over 1000-fold Rate Acceleration by Ethanol

Enzymes working in organic solvents are important for analytical chemistry, catalysis, and mechanistic studies. Although a few protein enzymes are highly active in organic solvents, little is known regarding nucleic acid-based enzymes. Herein, we report the first RNA-cleaving DNAzyme, named EtNa, th...

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Veröffentlicht in:Chembiochem : a European journal of chemical biology 2016-01, Vol.17 (2), p.159-163
Hauptverfasser: Zhou, Wenhu, Saran, Runjhun, Chen, Qingyun, Ding, Jinsong, Liu, Juewen
Format: Artikel
Sprache:eng
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