The divergent impact of COMT Val158Met on executive function in children with and without attention‐deficit/hyperactivity disorder

Children with attention‐deficit/hyperactivity disorder (ADHD) usually display deficits in executive function (EF), which are primarily mediated by prefrontal cortex (PFC). The functional polymorphism of catechol‐O‐methyltransferase (COMT), Val158Met (rs4680), leads to observed polymorphic difference...

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Veröffentlicht in:	Genes, brain and behavior brain and behavior, 2016-02, Vol.15 (2), p.271-279
Hauptverfasser:	Jin, J., Liu, L., Gao, Q., Chan, R. C. K., Li, H., Chen, Y., Wang, Y., Qian, Q.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADHD Adolescent Attention Deficit Disorder with Hyperactivity - genetics Catechol O-Methyltransferase - metabolism Child COMT development executive function Executive Function - physiology Female Genotype Humans Male Memory, Short-Term - physiology Neuropsychological Tests Polymorphism, Genetic - genetics Prefrontal Cortex - metabolism Val158Met
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