Differential gene expression of activating Fcγ receptor classifies active tuberculosis regardless of human immunodeficiency virus status or ethnicity

New diagnostics and vaccines for tuberculosis (TB) are urgently needed, but require an understanding of the requirements for protection from/susceptibility to TB. Previous studies have used unbiased approaches to determine gene signatures in single-site populations. The present study utilized a targ...

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Veröffentlicht in:	Clinical microbiology and infection 2014-04, Vol.20 (4), p.O230-O238
Hauptverfasser:	Sutherland, J.S., Loxton, A.G., Haks, M.C., Kassa, D., Ambrose, L., Lee, J.-S., Ran, L., van Baarle, D., Maertzdorf, J., Howe, R., Mayanja-Kizza, H., Boom, W.H., Thiel, B.A., Crampin, A.C., Hanekom, W., Ota, M.O.C., Dockrell, H., Walzl, G., Kaufmann, S.H.E., Ottenhoff, T.H.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Africa South of the Sahara Biomarkers - blood Biosignature Blood Ethnicity Female Gene Expression Gene Expression Profiling HIV Infections - complications Human immunodeficiency virus Humans Lentivirus Male Middle Aged Mycobacterium Receptors, IgG - blood Retroviridae RT-MLPA tuberculosis Tuberculosis - diagnosis Young Adult
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