Two Metabolites with DNA-Binding Affinity from the Mangrove Fungus Xylariasp. (#2508) from the South China Sea Coast
A novel metabolite xylopyridine A (1), together with a known compound pyrocoll (2), was isolated from mangrove endophytic fungus Xylaria sp. (#2508) collected from the South China Sea coast. Their structures were established on the basis of spectroscopic analysis, especially 2D‐NMR. Their affinities...
Gespeichert in:
| Veröffentlicht in: | Chinese journal of chemistry 2009-02, Vol.27 (2), p.365-368 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 368 |
|---|---|
| container_issue | 2 |
| container_start_page | 365 |
| container_title | Chinese journal of chemistry |
| container_volume | 27 |
| creator | XU, Fang PANG, Jiyan LU, Bingtai WANG, Jiajun ZHANG, Yi SHE, Zhigang VRIJMOED, L. L. P. GARETH JONES, E. B. LIN, Yongcheng |
| description | A novel metabolite xylopyridine A (1), together with a known compound pyrocoll (2), was isolated from mangrove endophytic fungus Xylaria sp. (#2508) collected from the South China Sea coast. Their structures were established on the basis of spectroscopic analysis, especially 2D‐NMR. Their affinities toward calf thymus (CT) DNA were studied by fluorescence quenching and spectrophotometric titration experiments. The results indicate that 1 showes strong DNA‐binding affinity presumably via an intercalation mechanism, thus it is exploitable as strong DNA‐binders.
A novel metabolite xylopyridine A (1), together with a known compound pyrocoll (2), was isolated from mangrove endophytic fungus Xylaria sp. (#2508) collected from the South China Sea coast. Their affinities toward calf thymus (CT) DNA were studied by fluorescence quenching and spectrophotometric titration experiments. |
| doi_str_mv | 10.1002/cjoc.200990059 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_wiley</sourceid><recordid>TN_cdi_proquest_miscellaneous_1776649915</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1776649915</sourcerecordid><originalsourceid>FETCH-LOGICAL-i1219-f6b555d3f524efe853fbf3b5193123fc9a162e5d3c0a29fdd0c71f61ce06f9533</originalsourceid><addsrcrecordid>eNpFkEtPAjEUhSdGExXdum7iBheDty1t7RJHwbcm-No1ZWihOExx2hH5947B4Oqem3zfWZwkOcLQwQDkNJ_5vEMApARgcivZwxx3UwGcbTcZAKccuu-7yX4Is4YXgvC9JD4vPbo3UY984aIJaOniFF089NJzV45dOUE9a13p4grZys9RnBp0r8tJ5b8M6tflpA7ofVXoyumw6KD2MWFwdvLPDn3d9GVTV2o0NBplXod4kOxYXQRz-HdbyUv_8jm7Su8eB9dZ7y51mGCZWj5ijI2pZaRrrDlj1I4sHTEsKSbU5lJjTkwD5KCJtOMx5AJbjnMD3EpGaStpr3sXlf-sTYhq7kJuikKXxtdBYSE470qJWYPKNbp0hVmpReXmulopDOp3W_W7rdpsq7Kbx2zzNW66dl2I5nvj6upDcUEFU28PAzW8eSJEwKu6pT-UpH4U</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1776649915</pqid></control><display><type>article</type><title>Two Metabolites with DNA-Binding Affinity from the Mangrove Fungus Xylariasp. (#2508) from the South China Sea Coast</title><source>Wiley Online Library All Journals</source><creator>XU, Fang ; PANG, Jiyan ; LU, Bingtai ; WANG, Jiajun ; ZHANG, Yi ; SHE, Zhigang ; VRIJMOED, L. L. P. ; GARETH JONES, E. B. ; LIN, Yongcheng</creator><creatorcontrib>XU, Fang ; PANG, Jiyan ; LU, Bingtai ; WANG, Jiajun ; ZHANG, Yi ; SHE, Zhigang ; VRIJMOED, L. L. P. ; GARETH JONES, E. B. ; LIN, Yongcheng</creatorcontrib><description>A novel metabolite xylopyridine A (1), together with a known compound pyrocoll (2), was isolated from mangrove endophytic fungus Xylaria sp. (#2508) collected from the South China Sea coast. Their structures were established on the basis of spectroscopic analysis, especially 2D‐NMR. Their affinities toward calf thymus (CT) DNA were studied by fluorescence quenching and spectrophotometric titration experiments. The results indicate that 1 showes strong DNA‐binding affinity presumably via an intercalation mechanism, thus it is exploitable as strong DNA‐binders.
A novel metabolite xylopyridine A (1), together with a known compound pyrocoll (2), was isolated from mangrove endophytic fungus Xylaria sp. (#2508) collected from the South China Sea coast. Their affinities toward calf thymus (CT) DNA were studied by fluorescence quenching and spectrophotometric titration experiments.</description><identifier>ISSN: 1001-604X</identifier><identifier>EISSN: 1614-7065</identifier><identifier>DOI: 10.1002/cjoc.200990059</identifier><language>eng</language><publisher>Weinheim: WILEY-VCH Verlag</publisher><subject>CT DNA-binding ; fluorescence ; fungus ; isolation ; metabolite ; xylopyridine A</subject><ispartof>Chinese journal of chemistry, 2009-02, Vol.27 (2), p.365-368</ispartof><rights>Copyright © 2009 SIOC, CAS, Shanghai & WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fcjoc.200990059$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fcjoc.200990059$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1413,27906,27907,45556,45557</link.rule.ids></links><search><creatorcontrib>XU, Fang</creatorcontrib><creatorcontrib>PANG, Jiyan</creatorcontrib><creatorcontrib>LU, Bingtai</creatorcontrib><creatorcontrib>WANG, Jiajun</creatorcontrib><creatorcontrib>ZHANG, Yi</creatorcontrib><creatorcontrib>SHE, Zhigang</creatorcontrib><creatorcontrib>VRIJMOED, L. L. P.</creatorcontrib><creatorcontrib>GARETH JONES, E. B.</creatorcontrib><creatorcontrib>LIN, Yongcheng</creatorcontrib><title>Two Metabolites with DNA-Binding Affinity from the Mangrove Fungus Xylariasp. (#2508) from the South China Sea Coast</title><title>Chinese journal of chemistry</title><addtitle>Chin. J. Chem</addtitle><description>A novel metabolite xylopyridine A (1), together with a known compound pyrocoll (2), was isolated from mangrove endophytic fungus Xylaria sp. (#2508) collected from the South China Sea coast. Their structures were established on the basis of spectroscopic analysis, especially 2D‐NMR. Their affinities toward calf thymus (CT) DNA were studied by fluorescence quenching and spectrophotometric titration experiments. The results indicate that 1 showes strong DNA‐binding affinity presumably via an intercalation mechanism, thus it is exploitable as strong DNA‐binders.
A novel metabolite xylopyridine A (1), together with a known compound pyrocoll (2), was isolated from mangrove endophytic fungus Xylaria sp. (#2508) collected from the South China Sea coast. Their affinities toward calf thymus (CT) DNA were studied by fluorescence quenching and spectrophotometric titration experiments.</description><subject>CT DNA-binding</subject><subject>fluorescence</subject><subject>fungus</subject><subject>isolation</subject><subject>metabolite</subject><subject>xylopyridine A</subject><issn>1001-604X</issn><issn>1614-7065</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><recordid>eNpFkEtPAjEUhSdGExXdum7iBheDty1t7RJHwbcm-No1ZWihOExx2hH5947B4Oqem3zfWZwkOcLQwQDkNJ_5vEMApARgcivZwxx3UwGcbTcZAKccuu-7yX4Is4YXgvC9JD4vPbo3UY984aIJaOniFF089NJzV45dOUE9a13p4grZys9RnBp0r8tJ5b8M6tflpA7ofVXoyumw6KD2MWFwdvLPDn3d9GVTV2o0NBplXod4kOxYXQRz-HdbyUv_8jm7Su8eB9dZ7y51mGCZWj5ijI2pZaRrrDlj1I4sHTEsKSbU5lJjTkwD5KCJtOMx5AJbjnMD3EpGaStpr3sXlf-sTYhq7kJuikKXxtdBYSE470qJWYPKNbp0hVmpReXmulopDOp3W_W7rdpsq7Kbx2zzNW66dl2I5nvj6upDcUEFU28PAzW8eSJEwKu6pT-UpH4U</recordid><startdate>200902</startdate><enddate>200902</enddate><creator>XU, Fang</creator><creator>PANG, Jiyan</creator><creator>LU, Bingtai</creator><creator>WANG, Jiajun</creator><creator>ZHANG, Yi</creator><creator>SHE, Zhigang</creator><creator>VRIJMOED, L. L. P.</creator><creator>GARETH JONES, E. B.</creator><creator>LIN, Yongcheng</creator><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>BSCLL</scope><scope>7TM</scope><scope>M7N</scope></search><sort><creationdate>200902</creationdate><title>Two Metabolites with DNA-Binding Affinity from the Mangrove Fungus Xylariasp. (#2508) from the South China Sea Coast</title><author>XU, Fang ; PANG, Jiyan ; LU, Bingtai ; WANG, Jiajun ; ZHANG, Yi ; SHE, Zhigang ; VRIJMOED, L. L. P. ; GARETH JONES, E. B. ; LIN, Yongcheng</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i1219-f6b555d3f524efe853fbf3b5193123fc9a162e5d3c0a29fdd0c71f61ce06f9533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>CT DNA-binding</topic><topic>fluorescence</topic><topic>fungus</topic><topic>isolation</topic><topic>metabolite</topic><topic>xylopyridine A</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>XU, Fang</creatorcontrib><creatorcontrib>PANG, Jiyan</creatorcontrib><creatorcontrib>LU, Bingtai</creatorcontrib><creatorcontrib>WANG, Jiajun</creatorcontrib><creatorcontrib>ZHANG, Yi</creatorcontrib><creatorcontrib>SHE, Zhigang</creatorcontrib><creatorcontrib>VRIJMOED, L. L. P.</creatorcontrib><creatorcontrib>GARETH JONES, E. B.</creatorcontrib><creatorcontrib>LIN, Yongcheng</creatorcontrib><collection>Istex</collection><collection>Nucleic Acids Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><jtitle>Chinese journal of chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>XU, Fang</au><au>PANG, Jiyan</au><au>LU, Bingtai</au><au>WANG, Jiajun</au><au>ZHANG, Yi</au><au>SHE, Zhigang</au><au>VRIJMOED, L. L. P.</au><au>GARETH JONES, E. B.</au><au>LIN, Yongcheng</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Two Metabolites with DNA-Binding Affinity from the Mangrove Fungus Xylariasp. (#2508) from the South China Sea Coast</atitle><jtitle>Chinese journal of chemistry</jtitle><addtitle>Chin. J. Chem</addtitle><date>2009-02</date><risdate>2009</risdate><volume>27</volume><issue>2</issue><spage>365</spage><epage>368</epage><pages>365-368</pages><issn>1001-604X</issn><eissn>1614-7065</eissn><abstract>A novel metabolite xylopyridine A (1), together with a known compound pyrocoll (2), was isolated from mangrove endophytic fungus Xylaria sp. (#2508) collected from the South China Sea coast. Their structures were established on the basis of spectroscopic analysis, especially 2D‐NMR. Their affinities toward calf thymus (CT) DNA were studied by fluorescence quenching and spectrophotometric titration experiments. The results indicate that 1 showes strong DNA‐binding affinity presumably via an intercalation mechanism, thus it is exploitable as strong DNA‐binders.
A novel metabolite xylopyridine A (1), together with a known compound pyrocoll (2), was isolated from mangrove endophytic fungus Xylaria sp. (#2508) collected from the South China Sea coast. Their affinities toward calf thymus (CT) DNA were studied by fluorescence quenching and spectrophotometric titration experiments.</abstract><cop>Weinheim</cop><pub>WILEY-VCH Verlag</pub><doi>10.1002/cjoc.200990059</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1001-604X |
| ispartof | Chinese journal of chemistry, 2009-02, Vol.27 (2), p.365-368 |
| issn | 1001-604X 1614-7065 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1776649915 |
| source | Wiley Online Library All Journals |
| subjects | CT DNA-binding fluorescence fungus isolation metabolite xylopyridine A |
| title | Two Metabolites with DNA-Binding Affinity from the Mangrove Fungus Xylariasp. (#2508) from the South China Sea Coast |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-17T11%3A10%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_wiley&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Two%20Metabolites%20with%20DNA-Binding%20Affinity%20from%20the%20Mangrove%20Fungus%20Xylariasp.%20(%232508)%20from%20the%20South%20China%20Sea%20Coast&rft.jtitle=Chinese%20journal%20of%20chemistry&rft.au=XU,%20Fang&rft.date=2009-02&rft.volume=27&rft.issue=2&rft.spage=365&rft.epage=368&rft.pages=365-368&rft.issn=1001-604X&rft.eissn=1614-7065&rft_id=info:doi/10.1002/cjoc.200990059&rft_dat=%3Cproquest_wiley%3E1776649915%3C/proquest_wiley%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1776649915&rft_id=info:pmid/&rfr_iscdi=true |