MicroRNAs Form Triplexes with Double Stranded DNA at Sequence-Specific Binding Sites; a Eukaryotic Mechanism via which microRNAs Could Directly Alter Gene Expression: e1004744

MicroRNAs are important regulators of gene expression, acting primarily by binding to sequence-specific locations on already transcribed messenger RNAs (mRNA) and typically down-regulating their stability or translation. Recent studies indicate that microRNAs may also play a role in up-regulating mR...

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Veröffentlicht in:	PLoS computational biology 2016-02, Vol.12 (2)
Hauptverfasser:	Paugh, Steven W, Coss, David R, Bao, Ju, Laudermilk, Lucas T, Grace, Christy R, Ferreira, Antonio M, Waddell, M Brett, Ridout, Granger, Naeve, Deanna, Leuze, Michael, LoCascio, Philip F, Panetta, John C, Wilkinson, Mark R, Pui, Ching-Hon, Naeve, Clayton W, Uberbacher, Edward C, Bonten, Erik J, Evans, William E
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Binding sites Cancer Deoxyribonucleic acid DNA DNA methylation Gene expression Genomes Grants Leukemia MicroRNAs Operating systems Zebrafish
Online-Zugang:	Volltext
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