Regulatory T cells can prevent memory CD8 super(+) T-cell-mediated rejection following polymorphonuclear cell depletion

Accumulating evidence suggests that alloreactive memory T cells (Tm) may form a barrier to tolerance induction in large animals and humans due in part to a resistance to suppression by Treg. However, why Tm are resistant to regulation and how the Tm response to an allograft differs from that of naiv...

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Veröffentlicht in:	European journal of immunology 2010-11, Vol.40 (11), p.3107-3116
Hauptverfasser:	Jones, Nick D, Brook, Matthew O, Carvalho-Gaspar, Manuela, Luo, Shiqao, Wood, Kathryn J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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