Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy

The macrophage is known to be a multifunctional antigen presenting cells and playing a central role in inflammation. Macrophages infiltrate into malignant tumor tissues in high numbers (the so-called tumor-associated macrophages [TAMs]) and many studies over the past decade have demonstrated that ma...

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Veröffentlicht in:	Advanced drug delivery reviews 2016-04, Vol.99 (Pt B), p.180-185
Hauptverfasser:	Komohara, Yoshihiro, Fujiwara, Yukio, Ohnishi, Koji, Takeya, Motohiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - pharmacology Antineoplastic Agents - therapeutic use Disease Progression Heterogeneity Humans Inflammation - pathology Macrophages - drug effects Macrophages - pathology Neoplasm Invasiveness - pathology Neoplasm Metastasis - pathology Neoplasms - drug therapy Neoplasms - pathology Polarization Protumor macrophage
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