Landscape of Long Noncoding RNAs in Psoriatic and Healthy Skin

We used RNA sequencing to study and characterize the long noncoding RNA (lncRNA) transcriptome in lesional skin from psoriasis patients before (PP) and after treatment (PT) with adalimumab and in normal skin from healthy individuals (NN). To this end, we sequenced total RNA from 18 psoriasis patient...

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Veröffentlicht in:	Journal of investigative dermatology 2016-03, Vol.136 (3), p.603-609
Hauptverfasser:	Gupta, Rashmi, Ahn, Richard, Lai, Kevin, Mullins, Elizabeth, Debbaneh, Maya, Dimon, Michelle, Arron, Sarah, Liao, Wilson
Format:	Artikel
Sprache:	eng
Schlagworte:	Adalimumab - administration & dosage Adult Biopsy, Needle Case-Control Studies Female Gene Expression Profiling Humans Immunohistochemistry Male Middle Aged Psoriasis - drug therapy Psoriasis - genetics Psoriasis - pathology Real-Time Polymerase Chain Reaction - methods Reference Values RNA, Long Noncoding - genetics RNA, Messenger - metabolism Sequence Analysis, RNA - methods Severity of Illness Index Transcriptome Young Adult
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